The incidence of intrahepatic bile duct stones as primary cholelithiasis varies in different regions, though it decreases to some extent. Minimally invasive hepatectomy is the correct procedure for treating early intrahepatic bile duct stones. However, there are still many problems concerning the su...

Nucleos (t) ide analogs (NAs) have been successfully used for treatment of chronic hepatitis B. Hepatitis B virus (HBV) replication is now recognized as the key driver of liver injury and disease progression, so the primary aim of treatment for chronic HBV infection is to maximize sustained suppress...

Objective To analyze the clinical characteristics and prognosis of neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) in infants. Methods The clinical data of43 infants with NICCD in our hospital from July2011 to April2014 were collected. The diagnosis was confirmed by tandem mass...

Objective To investigate the incidence of neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) in neonates with idiopathic neonatal cholestasis (INC) in Nanjing, China, SLC25A13 gene mutations in these neonates, and clinical features. Methods A total of 152 neonates with INC, who we...

Objective To summarize the clinical application of laparoscopy combined with choledochoscopy for treatment of gallstones with common bile duct stones in primary hospitals. Methods The clinical data of 46 patients who were diagnosed as having gallstones with common bile duct stones and underwent lapa...

Objective To investigate the relationship between cholecystectomy and the subsequent occurrence of primary choledocholithiasis and to review the surgical treatment of primary choledocholithiasis. Methods The clinical data of 70 patients with forward common bile duct stones after cholecystectomy who ...

Objective To investigate the value and clinical application of posterior- anterior cystohepatic triangle dissection in laparoscopic cholecystectomy (LC) . Methods The medical records of 250 patients who underwent LC were reviewed. The clinical data, including operating time, amount of bleeding, and ...

Objective To investigate the advantage and safety of the concept of fast- track surgery (FTS) applied in perioperative patients with biliary calculi and liver cirrhosis. Methods Fifty- two patients undergoing operation for biliary calculi and liver cirrhosis from January2011 to September 2013 were i...

Objective To explore the clinical characteristics and surgical indications of polypoid lesions of the gallbladder (PLG) . Methods The clinical data of 331 patients with PLG who underwent surgery in Department of General Surgery from August 2008 to December2013 were analyzed retrospectively. Comparis...

Objective To investigate the clinical effect of different nutritional therapies on the immune function of patients with malignant obstructive jaundice after percutaneous transhepatic cholangiodrainage (PTCD) . Methods A total of 50 patients with malignant obstructive jaundice who were admitted to ou...

Objective To profile the types of bacteria in bile culture and study their antibiotic sensitivity pattern in patients with varying degrees of acute cholangitis and to provide data guidance for the prevention and treatment of bacterial infection. Methods The clinical data of230 patients with acute ch...

Objective To analyze and study the implication of dynamic changes in plasma CD62 Pamong patients with obstructive jaundice and cholecystolithiasis. Methods A total of 58 patients diagnosed with choledocholithiasis and jaundice were included in the obstructive jaundice group, and 50 patients were in ...

Objective To investigate the effects of Jinyinlidanling (JYLDL) on gallbladder volume, rate of gallstone formation, and the expression of G protein- coupled bile acid receptor (TGR5) in guinea pigs. Methods Seventy- two female guinea pigs were randomly divided into treatment groups, normal control g...

Objective To examine the occurrence and possible mechanism of hepatocyte apoptosis in acute biliary tract infection. Methods After adaptive feeding for seven days, 30 male rats were randomly divided into five groups (n = 6 each) , i. e., one control group injected with 0. 2 ml of saline through the ...

Objective To investigate the efficacy and safety of entecavir (ETV) combined with adefovir (ADV) in chronic hepatitis B (CHB) patients with high viral load. Methods Eighty CHB patients with high viral load who were admitted to our hospital from December2008 to December 2011 were equally and randomly...

Objective To investigate the factors related to negative conversion of HBsAg in patients with acute hepatitis B (AHB) . Methods A total of 106 AHB patients who were admitted to the Department of Infectious Diseases, Zhoukou Central Hospital from February 2007 to February 2013 were recruited. Liver f...

Objective To observe the prognostic impact of portal vein immunochemotherapy in patients after resection of primary hepatocellular carcinoma (HCC) . Methods A retrospective analysis was performed on the clinical data of 48 patients who received portal vein immunochemotherapy after resection of prima...

Objective To investigate the clinical characteristics, etiology, and prognosis of hypoxic hepatitis (HH) . Methods The medical records of 68 patients with HH admitted to our hospital from January 2002 to December 2012 were collected and reviewed. The common causes of HH were analyzed. The patients w...

Objective To analyze the diagnostic values of contrast- enhanced ultrasound (CEUS) and time- intensity curve (TIC) for alpha- fetoprotein (AFP) - negative hepatocellular carcinoma ( HCC) , AFP- positive HCC, and hepatic hemangioma. Methods Patients with a confirmed diagnosis from October 2012 to Oct...

Objective To summarize the experience in the treatment of severe interstitial pneumonia after liver transplantation. Methods A retrospective analysis was made on the clinical data of 8 cases of severe interstitial pneumonia after liver transplantation who were diagnosed and treated from May 2008 to ...