As an aging society, China has an increasing number of elderly patients (≥80 years) . Given the characteristics of pancreaticobiliary diseases in elderly patients, therapeutic endoscopic retrograde cholangiopancreatography (TERCP) has become the main approach for these patients. When TERCP is perfor...
The differential diagnosis of pancreatic head mass has been clinical difficulties. Endoscopic ultrasonography is now recognized as one of the sensitive and effective methods for the diagnosis of pancreatic diseases. This paper discusses the diagnostic performance of endoscopic ultrasonography for va...
Abstract: In recent years, with the continuous development of endoscopic and interventional techniques, many new devices and methods have been used in clinical practice, and the application of endoscopic retrograde cholangiopancreatography (ERCP) in biliary and pancreatic diseases has developed rapidly. This ...
Objective To evaluate the safety of endoscopic retrograde cholangiopancreatography (ERCP) in patients with cirrhosis. Methods A retrospective analysis was performed on the clinical data of 347 patients who were admitted to Beijing You'an Hospital and received ERCP from January 2010 to November 2013....
Objective To compare the efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) versus endoscopic therapy (ET) in reducing recurrent variceal hemorrhage in patients with cirrhosis. Methods Data from randomized controlled trials (RCTs) ranging from January 1st, 1970 to January 1s...
Objective To examine the efficacy of endoscopic variceal ligation (EVL) as a secondary prophylaxis for cirrhotic patients associated with esophageal varices, and to identify the risk factors for postoperative rebleeding. Methods A retrospective analysis was performed on the clinical data of cirrhoti...
Objective To compare the clinical efficacy of endoscopic variceal ligation versus pericardial devascularization in the treatment of portal hypertension. Methods The clinical data of 101 cirrhotic patients with gastroesophageal varices and variceal hemorrhage from January2010 to January 2012 were ana...
Objective To evaluate the clinical effects of laparoscopic hepatectomy (LH) versus open hepatectomy (OH) in treating liver metastasis of colon cancer. Methods Relevant literature published up to October 2014 was retrieved from databases including Pub Med, Medline, Embase, and Cochrane Library. Exten...
Objective To analyze the clinical effects of several different approaches to laparoscopic cholecystectomy. Methods A total of400 patients who received cholecystectomy in our hospital from January 2013 to September 2014 were divided into four groups according to the approaches to laparoscopy (n = 100...
Objective To investigate the safety and superiority of fast track surgery (FTS) in elderly patients during the perioperative period of laparoscopic cholecystectomy (LC) . Methods The clinical data of 124 elderly patients who underwent LC at the Department of General Surgery in our institution betwee...
Objective To evaluate the causes, diagnostic and therapeutic principles, and prevention of the perforation related to endoscopic retrograde cholangiopancreatography (ERCP) . Methods All patients who developed perforation after ERCP in the Central Hospital of Shanghai Jiading District from January 20...
Abstract: Objective To investigate the genetic polymorphisms in the estrogen receptor (ER) alpha gene at position 29 (ERα-29) in patients with chronic hepatitis B (CHB) from Han nationality and Hui minority populations in Gansu Province, China. Methods Polymorphisms of ERα-29 were analyzed in 84 Han and 84 Hu...
Abstract: Objective To investigate the distribution of hepatitis B virus (HBV) genotypes among patients in Xinjiang Uygur Autonomous Region, China, and to explore its association with liver cirrhosis. Methods HBV genotypes of 1018 hepatitis B patients were determined by PCR analysis. The relationship of HBV g...
Abstract: Objective To analyze the predictive factors for rapid virologic response (RVR) in patients with chronic hepatitis C (CHC) who received combination therapy with pegylated interferon (PEG-IFN) and ribavirin. Methods A total of 127 CHC patients who were admitted to our department from 2010 to 2012 and ...
Abstract: Objective To evaluate the clinical application of two generations of HCV nucleic acid quantitative kits: COBASAmpli Prep /COBASTaq Man HCV, v2. 0 and COBASAmpli Prep / COBASTaq Man HCV Test. Methods HCV RNA levels in 556 samples that were collected in our hospital were measured using the COBASA...
Abstract: Objective To investigate the effects of entecavir on liver fibrosis indices in patients with hepatogenous diabetes. Methods A total of 98 patients, who were admitted to our hospital from June 2008 to August 2013, were diagnosed with hepatitis B cirrhosis complicated by hepatogenous diabetes, and wer...
Abstract: Objective To determine platelet count (PLT) , mean platelet volume (MPV) , and hemodynamic changes in patients with cirrhotic portal hypertension (CPH) post splenectomy plus pericardial devascularization (SPPD) , and to assess the surgical effect on coagulation function. Methods A retrospective anal...
Objective To compare the clinical efficacy and adverse effects of metformin versus vitamin E in the treatment of nonalcoholic fatty liver disease (NAFLD) . Methods Randomized controlled trials (RCTs) of NAFLD treatment with metformin and vitamin E, which were published before April 10, 2014, were re...
Objective To investigate the effect of salvianolic acid B on hepatocyte apoptosis in rats with nonalcoholic steatohepatitis (NASH) and the efficacy of salvianolic acid B in the treatment of NASH. Methods Sixty clean male SD rats were randomly divided into control group, NASH model group, and salvian...
Objective To evaluate the therapeutic efficacy and toxicity of oxaliplatin (OXA) -based systemic chemotherapy in patients with advanced hepatocellular carcinoma (HCC) . Methods Thirty patients with advanced HCC admitted to our hospital from June 2009 to June 2013 were randomly divided into Cape OX g...
Abstract: Acute kidney injury is a common complication in patients with cirrhosis. It is characterized by a sudden drop in glomerular filtration rate, retention of metabolic waste products, water-electrolyte imbalance, and acid-base disturbance. It markedly increases mortality in cirrhotic patients. Therefore...
Abstract: Nonalcoholic fatty liver disease (NAFLD) / nonalcoholic steatohepatitis (NASH) has become one of the important causes of liver cirrhosis in the world and may be an important cause of unexplained liver cirrhosis in China. The mechanism of NAFLD progression and early diagnosis are described. The cause...
Abstract: Liver transplantation is an essential treatment of primary liver cancer, but the postoperative high risk of recurrence and metastasis has seriously affected the effect of liver transplantation. With the development of molecular biology, researchers have found numerous molecular markers potentially r...
Abstract: Liver nonparenchymal cells play a very important role in the liver. Recent studies on the role of liver nonparenchymal cells, such as Kupffer cells, hepatic sinusoidal endothelial cells, hepatic stellate cells, and dendritic cells, in hepatic ischemia-reperfusion injury (HIRI) are reviewed. This rev...