2015 No. 1

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Editorial

Traditional Chinese medicine treatment of liver diseases

Wang RongBing

2015, 31(1): 2-6. DOI: 10.3969/j.issn.1001-5256.2015.01.001

Abstract(3623)

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Abstract:
Traditional Chinese medicine(TCM) treatment of liver diseases is derived from the regulation of liver function including storing blood and governing the free flow of qi,in which functional systems such as modern digestion,endocrine,and the gut-liver axis are involved,and is established on modern hep...

Therapeutic guidelines

Chinese consensus on the medical diagnosis and treatment of chronic cholecystitis and gallstones (2014, Shanghai)

Editorial Board of Chinese Journal of Digestion

2015, 31(1): 7-11. DOI: 10.3969/j.issn.1001-5256.2015.01.002

Abstract(3924)

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Abstract:

Diagnosis and treatment of cholangiocarcinoma: surgical expert consensus

Chinese Chapter of International Hepato-Pancreato-Biliary Association，Hepatic Surgery Group, Chinese Society of Surgery, Chinese Medical Association

2015, 31(1): 12-16. DOI: 10.3969/j.issn.1001-5256.2015.01.003

Abstract(3434)

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Abstract:

Guidelines for the management of acute pancreatitis(2014)

Group of Pancreas Surgery, Chinese Society of Surgery, Chinese Medical Association

2015, 31(1): 17-20. DOI: 10.3969/j.issn.1001-5256.2015.01.004

Abstract(275)

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Abstract:

Recommendations of ACG clinical guideline: the diagnosis and management of focal liver lesions

Zhu Peng, Chen Zhan, Wang YuMing

2015, 31(1): 21-24. DOI: 10.3969/j.issn.1001-5256.2015.01.005

Abstract(313)

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Abstract:

Expert interpretation of the “KASL Clinical Practice Guidelines: Management of hepatitis C”

Ding Yang, Dou XiaoGuang

2015, 31(1): 25-29. DOI: 10.3969/j.issn.1001-5256.2015.01.006

Abstract(247)

PDF (470KB)(132)

Abstract:

Interpretation of the practice guidelines for alcoholic liver disease by EASL in 2012 and AASLD in 2010

Chang BinXia, Sun Ying, Teng GuangJu, Zhang Wei, Zhao Jun, Zou ZhengSheng, Li BaoSen

2015, 31(1): 30-34. DOI: 10.3969/j.issn.1001-5256.2015.01.007

Abstract(2955)

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Abstract:

Discussions by experts

Strategy for traditional Chinese medicine prevention and treatment of chronic hepatitis B

Gao YueQiu

2015, 31(1): 35-37. DOI: 10.3969/j.issn.1001-5256.2015.01.008

Abstract(3022)

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Abstract:

Abundant experience has been accumulated when it comes to the traditional Chinese medicine(TCM) prevention and treatment of chronic hepatitis B(CHB).However,there still exist some deficiencies such as insufficient randomized controlled trials(RCTs) and lack of attention to objective indices for ther...

Progress and prospect of diagnosis and treatment of hepatic fibrosis by integrated traditional Chinese and Western medicine therapy

Wang XianBo, Sun Le

2015, 31(1): 38-41. DOI: 10.3969/j.issn.1001-5256.2015.01.009

Abstract(2969)

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Abstract:

In recent years,non-invasive methods for assessment of hepatic fibrosis have attracted more and more attention,and the application of non-invasive diagnostic techniques such as serum markers and transient elastography(Fibro Scan) for hepatic fibrosis is reviewed.Anti-fibrosis treatments should integ...

Clinical research progress in integrated traditional Chinese and Western medicine therapy for HBV-related liver failure

Li Jun

2015, 31(1): 42-47. DOI: 10.3969/j.issn.1001-5256.2015.01.010

Abstract(2968)

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Abstract:
Currently,hepatitis B virus(HBV)-related acute-on-chronic liver failure(ACLF) and chronic liver failure(CLF) are the main clinical types of liver failure.This disease has complex,changeable,and accompanying syndromes,so the treatment is very difficult.In recent years,some progress has been made in t...

Study on TCM syndromes of liver failure and yang-supporting therapy

Mao DeWen, Tang Nong, Wang Na, Wang Sha, Long FuLi, Yi MinMing

2015, 31(1): 48-51. DOI: 10.3969/j.issn.1001-5256.2015.01.011

Abstract(2836)

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Abstract:
This paper reviews traditional Chinese medicine(TCM) physicians' understanding of liver failure including its TCM causes,mechanisms,positions,and syndrome differentiation in various dynasties.The results suggest that modern researchers agree with ancient physicians on these aspects of liver failure....

Progress in integrated traditional Chinese and Western medicine diagnosis and treatment for advanced schistosomiasis

Wu Liang, Tian DeYing

2015, 31(1): 52-57. DOI: 10.3969/j.issn.1001-5256.2015.01.012

Abstract(2824)

PDF (1627KB)(606)

Abstract:
Schistosomiasis is a dangerous infectious disease,and advanced schistosomiasis is a serious harm to people' s lives and health.Anthelmintic treatment alone cannot effectively prevent the development and progression of advanced schistosomiasis,especially liver fibrosis.This article introduces the pat...

Original articles_Integrated traditional and western medicine on hepatopancteatobiliary disease

Effect of kidney-tonifying and spleen-strengthening prescription on PD-1 and PD-L1 expression in HBeAg-positive chronic hepatitis B patients with slightly increased ALT levels

Zhou ZhenHua, Sun XueHua, Li Man, Zhu XiaoJun, Jin ShuGen, Zhang Xin, Gao YaTing, Gao YueQiu

2015, 31(1): 58-62. DOI: 10.3969/j.issn.1001-5256.2015.01.013

Abstract(3127)

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Abstract:

Objective To study the effect of kidney-tonifying and spleen-strengthening prescription(KTSSP) on the expression of programmed death-1(PD-1) and programmed death-ligand 1(PD-L1) in HBe Ag-positive chronic hepatitis B(CHB) patients with slightly increased alanine aminotransferase(ALT) levels.Methods ...

Efficacy of glycyrrhizin in patients with chronic severe hepatitis B:a meta-analysis

Mao HaiYing, Kang Tao, Yao Ling, Chen Qin

2015, 31(1): 63-67. DOI: 10.3969/j.issn.1001-5256.2015.01.014

Abstract(2960)

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Abstract:

Objective To systematically evaluate the efficacy and safety of glycyrrhizin in patients with chronic severe hepatitis B.Methods Literature published from January 1990 to July 2014 were searched in databases including Pub Med,Cochrane Library,CBMdisc,CNKI,VIP,and Wanfang Data.The randomized controll...

Clinical efficacy of traditional Chinese medicine/herbal decoction combined with ursodeoxycholic acid for primary biliary cirrhosis:a meta-analysis

Du Ying, Fang Lei

2015, 31(1): 68-73. DOI: 10.3969/j.issn.1001-5256.2015.01.015

Abstract(3110)

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Abstract:

Objective To systematically evaluate the efficacy of traditional Chinese medicine / herbal decoction combined with ursodeoxycholic acid(UDCA) in the treatment of primary biliary cirrhosis(PBC),and to provide a reference for clinical medication.Methods Literature published before July 31,2014 was sea...

Clinical efficacy of Zisheng pills in treatment of adverse reactions in patients with primary hepatocellular carcinoma after transcatheter arterial chemoembolization

Liu XiaPing, Tao Yu, Wu ChunMing, Chen YongPing

2015, 31(1): 74-77. DOI: 10.3969/j.issn.1001-5256.2015.01.016

Abstract(2961)

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Abstract:

Objective To investigate the clinical efficacy of Zisheng pills in the treatment of adverse reactions in patients with primary hepatocellular carcinoma(HCC) after transcatheter arterial chemoembolization(TACE).Methods This study included 72 patients with liver cancer hospitalized in the Department o...

Efficacy of Chaowei Zhikangyin in treatment of rat model of non-alcoholic fatty liver disease

Xiong Yan, Zhang ZhiJuan, Liu Peng, Wang Ya

2015, 31(1): 78-81. DOI: 10.3969/j.issn.1001-5256.2015.01.017

Abstract(2687)

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Abstract:

Objective To observe the efficacy of Chaowei Zhikangyin in the treatment of the rat model of non-alcoholic fatty liver disease(NAFLD).Methods A rat model of NAFLD was established by feeding 50 Sprague-Dawley rats with high-fat diet for 6 weeks and was confirmed by liver pathological examination.Then...

Original articles_Fatty liver

An epidemiological survey of prevalence and risk factors for fatty liver disease in adults residing in Yan'an,China

Qiao LiNa, Dai GuangRong, Zhang Jin, Shen Ni

2015, 31(1): 82-87. DOI: 10.3969/j.issn.1001-5256.2015.01.018

Abstract(2176)

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Abstract:

Objective To investigate the prevalence and major risk factors for fatty liver disease among adult residents in Yan'an,Shanxi Province,China.Methods The study enrolled healthy adults who had physical examination with complete clinical records in our hospital from February 2011 to March 2013.All part...

Original articles_Biliary diseases

Expression and significance of UCP-2 in rats with obstructive jaundice and bile flow restoration

Wen Nuan, Zhu YiXiang, Lu: RenGeng, Kang JiangHui, Han HongJun, Xu HanBin

2015, 31(1): 88-92. DOI: 10.3969/j.issn.1001-5256.2015.01.019

Abstract(2128)

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Abstract:

Objective To investigate the expression and significance of uncoupling protein 2(UCP-2) in rats with obstructive jaundice and bile flow restoration,and to explore the molecular mechanisms of metabolic disorders and oxidative damage caused by obstructive jaundice.Methods Thirty-six healthy male Wista...

Original articles_Hepatopancreatobiliary tumor

Diagnostic value of combined determination of DNA ploidy level and miRNA-21 expression in ascites cells for hepatocellular carcinoma

Xiao ZuoHan, Meng Gang, Wang LiZhi, Sun WenJin

2015, 31(1): 93-98. DOI: 10.3969/j.issn.1001-5256.2015.01.020

Abstract(2921)

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Abstract:

Objective To evaluate the diagnostic value of combined determination of DNA ploidy level and microRNA-21(miRNA-21)expression in ascites cells for hepatocellular carcinoma(HCC).Methods A total of 117 patients with ascites admitted to our hospital from January 1,2012 to January 1,2014 were enrolled.Th...

Clinical effect of transcatheter arterial chemoembolization combined with argon-helium cryoablation in patients with advanced unresectable primary hepatocellular carcinoma

Ni MingLi

2015, 31(1): 99-102. DOI: 10.3969/j.issn.1001-5256.2015.01.021

Abstract(2803)

PDF (1625KB)(519)

Abstract:

Objective To evaluate the efficacy and safety of transcatheter arterial chemoembolization(TACE) combined with argon-helium cryoablation in patients with advanced unresectable primary hepatocellular carcinoma(HCC).Methods TACE was performed in 35 patients with primary HCC who were admitted to our hos...

Original articles_Others

Diagnosis and treatment of pyogenic liver abscess in elderly patients by multislice CT

Wang YuLin, Hu RongKui, Zong Min

2015, 31(1): 103-106. DOI: 10.3969/j.issn.1001-5256.2015.01.022

Abstract(2174)

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Abstract:

Objective To review the multislice computed tomography(MSCT) characteristics and treatment of pyogenic liver abscess in elderly patients.Methods A retrospective analysis was performed on the clinical data of 42 elderly patients who were diagnosed with pyogenic liver abscess in our hospital from Marc...

Brief reports

Efficacy of low-dose interferon α-1b combined with ribavirin and thymosin α1 versus standard treatment for chronic hepatitis C: a comparative study

Sun JianMin

2015, 31(1): 107-109. DOI: 10.3969/j.issn.1001-5256.2015.01.023

Abstract(1877)

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Abstract:

Case reports

Liver damage induced by Polygonum multiflorum powder: a report of 2 cases

Liu MiaoMiao, Pan LiuLan, Wei YuTong, Xiao HeJun, Duan LiWei

2015, 31(1): 110-111. DOI: 10.3969/j.issn.1001-5256.2015.01.024

Abstract(2659)

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Abstract:

A case of primary leiomyosarcoma of the liver and literature review

Liu ChunHua, Li QingYan, Guan Shan, Wang SiKui

2015, 31(1): 112-114. DOI: 10.3969/j.issn.1001-5256.2015.01.025

Abstract(2617)

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Abstract:

Reviews

HCV culture system and its application in antiviral research on Chinese herb extracts in vitro

Li JingTao, Chang ZhanJie, Xi Qi, Liu YaZhu, Song ChunRong, Nan Ran, Li RiXiang, Wei HaiLiang, Yan ShuGuang

2015, 31(1): 115-117. DOI: 10.3969/j.issn.1001-5256.2015.01.026

Abstract(1945)

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Abstract:
Many studies have shown that Chinese herb extracts could treat patients who suffer hepatitis C.However,the clinical efficacy is limited due to the use of traditional Chinese medicine(TCM) compounds.Because each drug contains multiple active substances,some of which may even act against each other in...

Research advances in traditional Chinese medicine combined with interventional therapy for hepatocellular carcinoma

Liu Yang, Li GuiYing, Zhao XiangXuan, Lu ZaiMing, Guo QiYong

2015, 31(1): 118-122. DOI: 10.3969/j.issn.1001-5256.2015.01.027

Abstract(2805)

PDF (1791KB)(632)

Abstract:
Interventional therapy has become the first choice of non-surgical treatment for hepatocellular carcinoma(HCC) due to its advantages such as little trauma and marked local effect.However,the clinical efficiency is less than expected.One of the possibilities is the resistance of cancer cells to anti-...

New progress in development of animal models of hepatitis C virus infection

Zhu Ting, Nie QingHe

2015, 31(1): 123-126. DOI: 10.3969/j.issn.1001-5256.2015.01.028

Abstract(2889)

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Abstract:
An animal model of hepatitis C virus(HCV) infection involves the use of an animal to build the model for simulating the whole process of HCV infection in humans.Establishing an ideal animal model for HCV infection is conducive to study on the pathogenesis of chronic hepatitis C,including virus-host ...

Relationship between intestinal microflora imbalance and nonalcoholic fatty liver disease

Ma RuiJuan, Wu Jing, Zhou YongNing

2015, 31(1): 127-129. DOI: 10.3969/j.issn.1001-5256.2015.01.029

Abstract(3002)

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Abstract:
The intestinal microecosystem is composed of natural microflora,intestinal epithelial cells,and intestinal mucosal immune system.Nonalcoholic fatty liver disease(NAFLD) is a metabolic stress-induced liver injury associated with insulin resistance and genetic susceptibility.In recent years,there has ...

Molecular targeted therapy for hepatocellular carcinoma

Shen YiNan, Lu JunHua

2015, 31(1): 130-134. DOI: 10.3969/j.issn.1001-5256.2015.01.030

Abstract(2589)

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Abstract:
Hepatocellular carcinoma(HCC) is the most common malignancy in the liver,for which surgical operation remains the primary treatment.However,the surgical treatment is associated with low resection rate and high recurrence rate,which drive studies on the molecule mechanism of initiation,metastasis,and...

Research progress in prediction of clinical outcome in patients with liver failure

Tang ShanHong, Zeng WeiZheng, Jiang MingDe, Fan QuanShui

2015, 31(1): 135-138. DOI: 10.3969/j.issn.1001-5256.2015.01.031

Abstract(2748)

PDF (1544KB)(535)

Abstract:
Liver failure is a clinical syndrome with severe disorders of liver cells for biosynthesis,detoxication,excretion,and biological transformation,which presents with coagulation disorders,jaundice,hepatic encephalopathy,and ascites.Liver failure progresses rapidly,so the prediction of clinical outcome...

Main applications of diffusion-weighted magnetic resonance imaging in liver diseases

Chen Juan, Yin HuaBin

2015, 31(1): 139-142. DOI: 10.3969/j.issn.1001-5256.2015.01.032

Abstract(2564)

PDF (1552KB)(564)

Abstract:

Liver failure is a clinical syndrome with severe disorders of liver cells for biosynthesis,detoxication,excretion,and biological transformation,which presents with coagulation disorders,jaundice,hepatic encephalopathy,and ascites.Liver failure progresses rapidly,so the prediction of clinical outcome...