Objective To investigate the risk factors for early rebleeding from esophageal and gastric varices ( EGV) in patients with liver cirrhosis. Methods A total of 432 patients with liver cirrhosis who were admitted to Ningxia Medical University from January 2006 to December 2009 were included in the study. These patients were divided into control group ( n = 325) , who stopped bleeding after initial treatment, and study group ( n = 107) , who had rebleeding after initial treatment. The clinical and test data of the two groups were analyzed.Comparison of measurement data between the two groups was made by t test, while comparison of enumeration data was made by chi- square test; multiple comparison of constituent ratios was made. The univariate unconditional logistic regression model was used for analyzing the risk factors for rebleeding. Results There were significant differences in sex, smoking, hemoglobin ( Hb) level, white blood cell ( WBC) count, alanine aminotransferase level, aspartate aminotransferase level, and spleen thickness between the two groups ( P < 0. 05) . The univariate unconditional logistic regression analysis showed that percentage of neutrophils ( OR = 0. 976, P = 0. 034) , WBC count ( OR =1. 173, P = 0. 007) , portal vein width ( OR = 7. 530, P = 0. 001) , and Hb level ( OR = 1. 415, P = 0. 013) were positively correlated with rebleeding. Conclusion WBC count, percentage of neutrophils, Hb level, and portal vein width are positively correlated with rebleeding from EGV, and they are the risk factors for early rebleeding from EGV in patients with liver cirrhosis if their values are high.
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