A systematic analysis of the application of diagnostic criteria for drug-induced liver injury in China based on the literature

Zhang Dong; Zhang Tao; Wu YuNan; Sun KeWei

doi:10.3969/j.issn.1001-5256.2017.05.026

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May 2017

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Article Navigation > Journal of Clinical Hepatology > 2017 > 33(5): 919-923

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A systematic analysis of the application of diagnostic criteria for drug-induced liver injury in China based on the literature

DOI: 10.3969/j.issn.1001-5256.2017.05.026

Graduate School, Hunan University of Chinese Medicine

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Published Date: 2017-05-20

Abstract

Abstract

Objective To investigate the application of diagnostic criteria for drug-induced liver injury in China.Methods CNKI, VIP, and Wanfang Data were searched for articles published from 1990 to 2015, and the diagnostic criteria in the articles were recorded to investigate the current application of diagnostic criteria for drug-induced liver injury.Results A total of 609 articles were included, with 410 articles of case studies and 199 case reports.A total of 15 types of diagnostic criteria were used in China, and only 13.4% of these articles used the causality assessment method recommended by the international community.In 46% of the cases reported in the articles, a diagnosis was made based on clinical symptoms and exclusion of common causes of liver injury.Conclusion There are many diagnostic criteria for drug-induced liver injury in China, and the diagnosis is subjective and lacks rigor.
- drug induced liver injury,
- diagnosis,
- reference standards

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References(35)

References

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A systematic analysis of the application of diagnostic criteria for drug-induced liver injury in China based on the literature

DOI: 10.3969/j.issn.1001-5256.2017.05.026

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A systematic analysis of the application of diagnostic criteria for drug-induced liver injury in China based on the literature

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