中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 7
Jul.  2011

The role of annexin A2 overexpression in the development and progression of hepatocellular carcinoma

Research funding:

 

  • Published Date: 2011-07-20
  • Annexin A2 can translocate to the outer membrane surface and activate correlative signaling pathway through assembling heterotetramer with S100A10, and can enter nucleus and participate in DNA synthesis and cell proliferation after its Ser25 is phosphorylated.It regulates angiogenesis, involves formation of hepatocellular carcinoma (HCC) , and affects the prognosis of HCC.This review summarizes recent studies of its molecular constitution, function and the values of diagnosis and prognosis for HCC.

     

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