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CN 22-1108/R
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2014 No. 8

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Editorial
Current status and thinking of diagnosis and treatment of severe acute pancreatitis
Li ZhaoShen, Du YiQi
2014, 30(8): 709-711. DOI: 10.3969/j.issn.1001-5256.2014.08.001
Abstract(2758) PDF (1462KB)(742)
Abstract:
The guidelines for the diagnosis and treatment of acute pancreatitis are the important reference for clinicians in treating acute pancreatitis, especially severe acute pancreatitis (SAP) .However, currently there is much discrepancy on the opinion and practice in China, which affects the treatment o...
Therapeutic guidelines
Diagnosis and treatment of acute pancreatitis:comparison and interpretation of the main guidelines in China and abroad
Zhang TaiPing, Cao Zhe, Zhao YuPei
2014, 30(8): 712-715. DOI: 10.3969/j.issn.1001-5256.2014.08.002
Abstract(303) PDF (208KB)(954)
Abstract:
A review of ISGPS consensus on definition and classification of post- pancreatic surgery complications
Yang GuiYuan, Qian ZhuYin
2014, 30(8): 716-718. DOI: 10.3969/j.issn.1001-5256.2014.08.003
Abstract(3283) PDF (1382KB)(632)
Abstract:
Recommendations on hepatic encephalopathy in chronic liver disease: 2014 practice guideline by the European Association for the Study of the Liver and the American Association for the Study of Liver Diseases
Zhang Ying, Liu Wei, Zhang FuKui
2014, 30(8): 719-721. DOI: 10.3969/j.issn.1001-5256.2014.08.004
Abstract(3747) PDF (1377KB)(1134)
Abstract:
Discussions by experts
Diagnosis and treatment of drug- induced pancreatitis
Qian JiaMing, Wang ShuJun
2014, 30(8): 722-725. DOI: 10.3969/j.issn.1001-5256.2014.08.005
Abstract(3494) PDF (1452KB)(649)
Abstract:
Drug- induced pancreatitis (DIP) belongs to gastrointestinal drug- induced diseases.With the wide use of drugs, the number of drugs that may induce DIP is increasing.Since there are not specific clinical indicators for detecting DIP or a complete diagnostic and therapeutic process for DIP, its diagn...
Clinical features and treatment of organ failure in severe acute pancreatitis
Cui LiJian, Liu RuiXia, Wang Yan, Yin ChengHong
2014, 30(8): 726-729. DOI: 10.3969/j.issn.1001-5256.2014.08.006
Abstract(3217) PDF (1410KB)(669)
Abstract:
Organ failure is an important factor causing death in patients with severe acute pancreatitis (SAP) .In recent years, thanks to the further study of pathophysiology of SAP and the continuous accumulation of experience and technology, substantial progress has been made in the diagnosis and treatment ...
Role of autophagy in development and progression of acute pancreatitis
Yang ShuLi, Liu Jie, Chen WeiChang
2014, 30(8): 730-733. DOI: 10.3969/j.issn.1001-5256.2014.08.007
Abstract(3008) PDF (1395KB)(658)
Abstract:
Acute pancreatitis is considered an autodigestive disorder in which inappropriate activation of trypsinogen to trypsin within pancreatic acinar cells leads to the development of pancreatitis.Autophagy is an evolutionarily preserved degradation process of cytoplasmic cellular constituents, and it is ...
Discussion of difficult problems of early diagnosis of pancreatic cancer
Guo XiaoZhong, Liu Xu
2014, 30(8): 734-736. DOI: 10.3969/j.issn.1001-5256.2014.08.008
Abstract(3357) PDF (1379KB)(657)
Abstract:
Pancreatic cancer is a common malignant neoplasm of the pancreas with an extremely high mortality.Currently, the early diagnosis of pancreatic cancer is still not ideal.Attention should be paid to some clinical warning symptoms, such as unexplained abdominal and back pain, jaundice, and unexpected d...
Research advances in relationship between diabetes and pancreatic cancer
He XiangYi, Yuan YaoZong
2014, 30(8): 737-739. DOI: 10.3969/j.issn.1001-5256.2014.08.009
Abstract(3074) PDF (1387KB)(608)
Abstract:
Pancreatic cancer (PC) is one of common malignant digestive diseases.It is mostly diagnosed at advanced stage, with an extremely poor progression.The relationship between diabetes and PC was shown by numerous epidemiological studies for decades.Retrospective clinical studies and research on molecula...
Development of optimal management of upper gastrointestinal bleeding secondary to pancreatic sinistral portal hypertension
Song Yang, Lu Hao, Liu QuanDa
2014, 30(8): 740-742. DOI: 10.3969/j.issn.1001-5256.2014.08.010
Abstract(3050) PDF (1478KB)(625)
Abstract:
The pathogenesis of pancreatic sinistral portal hypertension (PSPH) is quite different from that of cirrhotic portal hypertension, and PSPH is the only curable type of portal hypertension.Gastric variceal bleeding is a less common manifestation of PSPH;however, it probably exacerbates the patient's ...
Original articles_Pancreatic diseases
Clinical effect of endoscopic retrograde cholangiopancreatography in 80 elderly patients with biliary pancreatitis
Liu LianLian, Xu Hui, Wang Hua, Liu Yang, Zou ZeFang, Yang Na
2014, 30(8): 743-745. DOI: 10.3969/j.issn.1001-5256.2014.08.011
Abstract(2741) PDF (1385KB)(557)
Abstract:
Objective To investigate the safety and efficacy of endoscopic retrograde cholangiopancreatography (ERCP) treatment in elderly patients with biliary pancreatitis.Methods A retrospective analysis was performed on 80 elderly patients (more than 80 years old) with biliary pancreatitis who were admitted...
Clinical effect of endoscopic nasobiliary drainage in prevention of post- ERCP pancreatitis in patients with choledocholithiasis
Zhao XiaoWen, Bao JunJun, Hu Cui, Ding Hao, Xu ZhangWei, Liu XiaoChang, Mei Qiao, Xu JianMing
2014, 30(8): 746-748. DOI: 10.3969/j.issn.1001-5256.2014.08.012
Abstract(3009) PDF (1399KB)(521)
Abstract:
Objective To investigate the clinical effect of endoscopic nasobiliary drainage (ENBD) in the prevention of post- endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) and hyperamylasemia in patients with choledocholithiasis.Methods A total of 560 patients with choledocholithiasis...
Significance of postoperative structural changes in serum N- glycans in pancreatic cancer patients
Jin Yu, Zhan Chao, Zhang YuBao
2014, 30(8): 749-751. DOI: 10.3969/j.issn.1001-5256.2014.08.013
Abstract(2821) PDF (1432KB)(552)
Abstract:
Objective To investigate the structural changes in specific serum N- glycans in pancreatic cancer patients and to identify the specific serum maker of pancreatic cancer.Methods The pancreatic cancer patients who visited the Third Affiliated Hospital of Harbin Medical University from June 2011 to Dec...
Analysis of clinical significance of quantitative expression of VEGF mRNA and uPA mRNA in pancreatic cancer tissue
Xi PengCheng, Shi KaiWang, Zhu Xiang, Yang KunXing, Liu ZiJun, Bian JianMin, Zhao YouCai
2014, 30(8): 752-756. DOI: 10.3969/j.issn.1001-5256.2014.08.014
Abstract(2712) PDF (1601KB)(525)
Abstract:
Objective To investigate the clinical significance of quantitative expression of vascular endothelial growth factor (VEGF) mRNA and urokinase- type plasminogen activator (uPA) mRNA in pancreatic cancer tissue.Methods A retrospective study was conducted on the complete data of 30 patients with a path...
Original articles_Viral hepatitis
Association between IPS- 1 polymorphisms and PEG- IFN treatment response in patients with HBeAg- positive chronic hepatitis B
Wu HaiQing, Zhao GangDe, Li FengDi, Liu KeHui, Xu YuMin, Lin LanYi, Xie Qing, Wang Hui
2014, 30(8): 757-763. DOI: 10.3969/j.issn.1001-5256.2014.08.015
Abstract(2152) PDF (1686KB)(529)
Abstract:
Objective To investigate whether interferon- β promoter stimulator 1 (IPS- 1) gene polymorphisms could affect the treatment response to peginterferon alpha (PEG- IFN) in patients with HBeAg- positive chronic hepatitis B (CHB) .Methods A total of 212HBeAg- positive CHB patients treated with PEG- IFN ...
Original articles_Liver fibrosis and liver cirrhosis
Observation of dietary intervention on nutritional risk in patients with liver cirrhosis
Zhang Min, Hang Lei, Yuan XiaoJie, Yan HongQing
2014, 30(8): 764-767. DOI: 10.3969/j.issn.1001-5256.2014.08.016
Abstract(2303) PDF (1398KB)(570)
Abstract:
Objective To detect nutritional problems in liver cirrhosis patients early through nutritional risk screening, and to provide them with individual dietary intervention for improving their malnutrition and avoiding or reducing diet- related complications.Methods The nutritional risk of liver cirrhosi...
Original articles_Biliary diseases
Technical difficulties of laparoscopic common bile duct exploration and their countermeasures for patients with history of upper abdominal surgery
Mei Yong, Peng CiJun, Zhu HongJiang, Shu DeJun, Li WeiNan, Li XiongXiong
2014, 30(8): 768-771. DOI: 10.3969/j.issn.1001-5256.2014.08.017
Abstract(306) PDF (202KB)(67)
Abstract:
Objective To investigate the technical difficulties of laparoscopic common bile duct exploration (LCBDE) and their countermeasures for patients with a history of upper abdominal surgery.Methods A retrospective analysis was performed on the clinical data of 72 patients with a history of upper abdomin...
Clinical efficacy of transumbilical single- port laparoscopic cholecystectomy with ultrasonic knife for directly handling cystic artery
Gong JinWei, Xu Jun, Liu ChunFu
2014, 30(8): 772-775. DOI: 10.3969/j.issn.1001-5256.2014.08.018
Abstract(289) PDF (274KB)(69)
Abstract:
Objective To investigate the clinical feasibility and value of transumbilical single- port laparoscopic cholecystectomy with intraoperative ultrasonic knife for directly handling the cystic artery.Methods A retrospective analysis was performed on the clinical data of 231 patients who underwent lapar...
Role of Rouviere's sulcus as anatomical landmark in laparoscopic cholecystectomy:a report of 750 cases
Wang ShouJun, Wang Yue, Wang QingWen, Li HongXu, Song JinZhi, Hou JunCheng, Tang XueMei
2014, 30(8): 776-778. DOI: 10.3969/j.issn.1001-5256.2014.08.019
Abstract(619) PDF (186KB)(196)
Abstract:
Objective To explore the role of Rouviere's sulcus as the anatomical landmark for the cystic duct in laparoscopic cholecystectomy.Methods The clinical data of 750 patients who underwent laparoscopic cholecystectomy operated by one beginner from October 2012 to March 2014 in the Affiliated Santai Hos...
Original articles_Hepatopancreatobiliary tumor
CT and pathological features of primary hepatic angiosarcoma
Xing YaoYao, Xia CongYang
2014, 30(8): 779-781. DOI: 10.3969/j.issn.1001-5256.2014.08.020
Abstract(2510) PDF (1795KB)(466)
Abstract:

Objective To present the computed tomography (CT) findings and associated pathological features of eight cases of primary hepatic angiosarcoma (PHA) .Methods All cases were confirmed by pathology.After a CT scan of the upper abdomen, all cases of PHA underwent enhanced scans in the arterial phase, p...
Original articles_Others
Therapeutic effect of terlipressin combined with albumin in 24 patients with hepatorenal syndrome
Chen Si, Sun ZhangYu, Zhang ZhiHao, Wang YingYing
2014, 30(8): 782-784. DOI: 10.3969/j.issn.1001-5256.2014.08.021
Abstract(2687) PDF (1623KB)(503)
Abstract:

Objective To observe the therapeutic effect of terlipressin combined with albumin in management of patients with hepatorenal syndrome.Methods A retrospective study enrolling 46 patients with hepatorenal syndrome from May 2011 to August 2013 was conducted, in which 22 patients were allocated to contr...
Diagnostic values of GP73, AFP- L3, AFP, and AFU for liver diseases
Ding Yan, Li Dan, Wang NianYue, Geng QuanLin
2014, 30(8): 785-789. DOI: 10.3969/j.issn.1001-5256.2014.08.022
Abstract(2881) PDF (1510KB)(526)
Abstract:

Objective To compare the levels of Golgi glycoprotein 73 (GP73) , alpha- fetoprotein heterogeneity 3 (AFP- L3) , alpha-fetoprotein (AFP) , and α- L- fucosidase (AFU) between patients with different liver diseases and the diagnostic value of any or a combination of these makers for liver cancer.Metho...
Protective role and immunoregulatory effect of CXCR3 in hepatic ischemia- reperfusion injury
Gao Jun, Chen Gong, Lu: Long
2014, 30(8): 790-794. DOI: 10.3969/j.issn.1001-5256.2014.08.023
Abstract(2796) PDF (1829KB)(555)
Abstract:

Objective To investigate the role and action mechanism of chemokine (C- X- C motif) receptor 3 (CXCR3) in hepatic ischemia- reperfusion injury (IRI) .Methods Forty- eight mice were divided into operation group and sham- operation group.The operation group was treated to establish a mouse model of IR...
Brief reports
Bacterial liver abscess:a clinical analysis of 123 cases
Yu ZeYuan, Zhao RongRong, Jiao ZuoYi
2014, 30(8): 795-797. DOI: 10.3969/j.issn.1001-5256.2014.08.024
Abstract(1833) PDF (1386KB)(580)
Abstract:
Case reports
One case of autoimmune pancreatitis
Li WanYu, Qi Yue, Wu Na, Shi Yu, Cai YanJun
2014, 30(8): 798-800. DOI: 10.3969/j.issn.1001-5256.2014.08.025
Abstract(2680) PDF (1919KB)(603)
Abstract:
Gastrointestinal bleeding caused by pancreatic abscess and gastric fistula:a report of one case
Shang ZhenNing, Yuan QiuXia, Zhu LiNing
2014, 30(8): 801-802. DOI: 10.3969/j.issn.1001-5256.2014.08.026
Abstract(2688) PDF (1414KB)(541)
Abstract:
HBV infection with Budd- Chiari syndrome:a report of one case
Wu Qiong, Liu Na, Xu GuangHua
2014, 30(8): 803-804. DOI: 10.3969/j.issn.1001-5256.2014.08.027
Abstract(2797) PDF (1373KB)(583)
Abstract:
One case of hepatic amyloidosis
Zhu JuanJuan, Liu Qin, Mu Mao, Chen Jia, Wang NiuNiu, Li JunLi
2014, 30(8): 805-806. DOI: 10.3969/j.issn.1001-5256.2014.08.028
Abstract(2544) PDF (1463KB)(560)
Abstract:
Acute- on- chronic liver failure with brain abscess and pulmonary abscess caused by Sphingomonas paucimobilis:a report of one case
Sun Han, Xia Lin, Yin Fang, Zhou XinMin
2014, 30(8): 807-808. DOI: 10.3969/j.issn.1001-5256.2014.08.029
Abstract(2726) PDF (1379KB)(575)
Abstract:
Bile duct hamartoma misdiagnosed as multiple liver cysts:a report of one case
Wang SuNa, Liang ZhiJun, Kang Wen, Jia ZhanSheng, Bai XueFan, Xie YuMei, Hao ChunQiu
2014, 30(8): 809-810. DOI: 10.3969/j.issn.1001-5256.2014.03.030
Abstract(2791) PDF (1857KB)(523)
Abstract:
One case of vanishing bile duct syndrome
Ma LinYuan, Chen Qian, Hua Rui, Pan Yu
2014, 30(8): 811-812. DOI: 10.3969/j.issn.1001-5256.2014.08.031
Abstract(2154) PDF (1737KB)(519)
Abstract:
Academic contention
Several opinions on EASL recommendations on treatment of hepatitis C (April 2014)
Dai MingJia, Yan XueBing
2014, 30(8): 813-814. DOI: 10.3969/j.issn.1001-5256.2014.08.032
Abstract(217) PDF (248KB)(158)
Abstract:
Reviews
Pathogenetic mechanism of microcirculatory disturbance and treatment advances in acute pancreatitis
Hou Fei, Liu RuiXia, Yin ChengHong
2014, 30(8): 815-818. DOI: 10.3969/j.issn.1001-5256.2014.08.033
Abstract(3045) PDF (1412KB)(600)
Abstract:
In recent years, there has been increasing evidence that microcirculatory disturbance, including vasoconstriction, shunting, inadequate perfusion, increased blood viscosity, and coagulation, is closely associated with the pathogenesis of acute pancreatitis (AP) .These processes may be exacerbated by...
Significance and progress in detection of HBV cccDNA in peripheral blood mononuclear cells
Cai ShaoPing, Liu Ze, Xu DongPing
2014, 30(8): 819-821. DOI: 10.3969/j.issn.1001-5256.2014.08.034
Abstract(3213) PDF (1395KB)(516)
Abstract:
Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) is an intermediate replicative episome which is stable and not easy to eliminate.cccDNA serves as the template for HBV replication and plays an important role in persistence of HBV infection in hepatocytes, and it is also a biomarker of...
Progress in emergency management of esophageal variceal bleeding
Liu GuoFang, Xiang XiaoXing
2014, 30(8): 822-824. DOI: 10.3969/j.issn.1001-5256.2014.08.035
Abstract(2858) PDF (1389KB)(583)
Abstract:
Esophageal variceal bleeding is a severe complication of cirrhotic portal hypertension and the main cause of mortality in patients.Studies revealed no significant differences in emergency hemostasis rate, fatality rate, and rebleeding rate between patients receiving endoscopic treatment and vasoacti...
The role of intestinal endotoxemia in liver failure and its complications
Gao FangYuan, Wang XianBo
2014, 30(8): 825-828. DOI: 10.3969/j.issn.1001-5256.2014.08.036
Abstract(2831) PDF (1398KB)(510)
Abstract:
Recent studies have found that endotoxin not only activates immune response, exacerbates liver injury, and induces liver failure, but also plays an important role in the development of hepatic encephalopathy, hepatorenal syndrome, spontaneous bacterial peritonitis, and other fatal complications.The ...
Research advances in sorafenib combined with orthotopic liver transplantation, radiofrequency ablation, and transarterial chemoembolization in treatment of hepatocellular carcinoma
Zhang MingJuan, Liu Jia, Xiang XiaoXing, Wang Su
2014, 30(8): 829-832. DOI: 10.3969/j.issn.1001-5256.2014.08.037
Abstract(3062) PDF (1710KB)(565)
Abstract:
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide, and traditional surgery and chemotherapy provide limited benefit.Sorafenib, a multikinase inhibitor, was proved effective for advanced HCC in phase III clinical trial, which was a breakthrough in the treatment of HC...
Studies on PPAR α and γ participating in progression of liver fibrosis by regulating ACSL1
Xin Xuan, Yan HongZhu, Li WeiQing, Yu HongYu
2014, 30(8): 833-835. DOI: 10.3969/j.issn.1001-5256.2014.08.038
Abstract(429) PDF (183KB)(196)
Abstract:
During the development and procession of liver fibrosis, peroxisome proliferator- activated receptor (PPAR) α and γ are in charge of the regulation of lipid metabolism, fatty acid metabolism, anti- liver fibrosis, etc., and are closely related to fat metabolism- related enzymes.As a key enzyme in fa...
Application of metabolomics in research on biomarkers for hepatocellular carcinoma
Wang JianGang, Li HuaCheng, Fei XinYing
2014, 30(8): 836-838. DOI: 10.3969/j.issn.1001-5256.2014.08.039
Abstract(3164) PDF (1391KB)(504)
Abstract:
As a novel research tool, metabolomics technology can reveal the differences in metabolic profiles during the development and progression of hepatocellular carcinoma (HCC) , so it has been widely applied for research on HCC biomarkers.The significance of metabolomics in the diagnosis of HCC is brief...
    

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