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ISSN 2097-3497 (Online)
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2019 Vol. 35, No. 12

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Editorial
History and development of biliary surgery
Dou KeFeng, Li Xiao
2019, 35(12): 2617-2621. DOI: 10.3969/j.issn.1001-5256.2019.12.001
Abstract(1424) PDF (1964KB)(327)
Abstract:
Biliary surgery is the main branch of general surgery,which plays an important role in the field of surgery. The pathological and clinical manifestations of biliary diseases are very complex,so biliary surgery is still the most challenging surgery in the digestive system.With the development of mini...
Discussions by experts
Advances in the diagnosis and treatment of severe acute cholangitis
Wang RongFeng, Lu: Yi, Zhang XiaoGang
2019, 35(12): 2622-2626. DOI: 10.3969/j.issn.1001-5256.2019.12.002
Abstract(2001) PDF (1902KB)(375)
Abstract:
Severe acute cholangitis,also called acute obstructive suppurative cholangitis( AOSC),has acute onset and rapid progression and is the primary cause of death in patients with benign biliary tract diseases,especially in elderly patients,and it is often complicated by multiple system organ failure. Th...
Surgical management of bile duct injury
Ren Bin
2019, 35(12): 2627-2631. DOI: 10.3969/j.issn.1001-5256.2019.12.003
Abstract(1187) PDF (1884KB)(276)
Abstract:
Cholecystectomy is the most common cause of iatrogenic bile duct injury. The causes,classification and diagnosis of bile duct injury were analyzed. According to the different opportunity of bile duct injury,different treatment strategies and infection control were adopted. The selection of definitiv...
Advance and controversy of hilar cholangiocarcinoma
Li XiangCheng, Feng QinChao
2019, 35(12): 2632-2637. DOI: 10.3969/j.issn.1001-5256.2019.12.004
Abstract(1376) PDF (1912KB)(378)
Abstract:
Hilar cholangiocarcinoma is one of the most difficult malignant tumors in the biliary system. The best chance of treatment often absent on account of the portal vein and liver lobe are invaded. Although the efficacy of hilar cholangiocarcinoma improved with the development of diagnosis and surgical ...
Research advances in the clinical diagnosis of intrahepatic cholangiocarcinoma
Chen ZhiSheng, Tang ChenWei, Tang ChaoHui, Tong HuanJun, Jin ZhiWei
2019, 35(12): 2638-2643. DOI: 10.3969/j.issn.1001-5256.2019.12.005
Abstract(1638) PDF (1900KB)(347)
Abstract:
Intrahepatic cholangiocarcinoma( ICC) is a malignant liver tumor derived from the epithelial cells of the second-or higher-order branch of the bile duct,with the features of insidious early symptoms,high degree of malignancy,rapid disease progression,lymph node metastasis,intrahepatic metastasis,and...
Liver transplantation for the treatment of intrahepatic cholangiocarcinoma: Controversies and perspectives
Zhang HongTao, Tao KaiShan
2019, 35(12): 2644-2647. DOI: 10.3969/j.issn.1001-5256.2019.12.006
Abstract(1423) PDF (1877KB)(238)
Abstract:
Liver transplantation is the only effective method for the treatment of end-stage liver disease,but there are still controversies over its application in the treatment of intrahepatic cholangiocarcinoma( ICC). ICC has a high degree of malignancy,occult symptoms,and a lack of specific clinical manife...
Guidelines
Guidelines for the prevention and treatment of chronic hepatitis B (version 2019)
Chinese Society of Infectious Diseases, Chinese Medical Association, Chinese Society of Hepatology, Chinese Medical Association
2019, 35(12): 2648-2669. DOI: 10.3969/j.issn.1001-5256.2019.12.007
Abstract(9024) PDF (1198KB)(3509)
Abstract:

In order to achieve the goal of “eliminating viral hepatitis as a major public health threat by 2030”established by the World Health Organization,Chinese Society of Infectious Diseases and Chinese Society of Hepatology,Chinese Medical Association,organized related experts in 2019 to update and devel...
Guidelines for the prevention and treatment of hepatitis C(2019 version)
Chinese Society of Hepatology, Chinese Medical Association, Chinese Society of Infectious Diseases, Chinese Medical Association
2019, 35(12): 2670-2686. DOI: 10.3969/j.issn.1001-5256.2019.12.008
Abstract(1607) PDF (666KB)(1556)
Abstract:

In order to standardize and update the prevention,diagnosis and antiviral therapy of hepatitis C and to achieve the World Health Organization's goal of eliminating viral hepatitis as a public health threat by 2030,Chinese Medical Association,the Chinese Society of Hepatology,and the Society of Infec...
Guidelines for safe use of Polygoni Multiflori Radixl
Branch of Hepatobiliary Diseases, China Association of Chinese, Branch of Chinese Patent Medicine, China Association of Chinese Medicine, Professional Committee of Clinical Chinese Pharmacy , Chinese Pharmaceutical Association, , et al
2019, 35(12): 2687-2693. DOI: 10.3969/j.issn.1001-5256.2019.12.009
Abstract(1925) PDF (2142KB)(492)
Abstract:
CCI clinical practice guidelines: Management of TIPS for portal hypertension (2019 edition)
The Chinese College of Interventionalists
2019, 35(12): 2694-2699. DOI: 10.3969/j.issn.1001-5256.2019.12.010
Abstract(1996) PDF (309KB)(1173)
Abstract:

Portal hypertension( PH) is one of the main complications of cirrhosis. Transjugular intrahepatic portosystemic shunt( TIPS) is the percutaneous creation of a conduit from the hepatic vein to the portal vein that is used to manage consequences of PH( i. e.,variceal bleeding and refractory ascites) a...
Technical specifications for obtaining donor liver for liver transplantation in China (version 2019)
Chinese Society of Organ Transplantation, Chinese Medical Association
2019, 35(12): 2700-2702. DOI: 10.3969/j.issn.1001-5256.2019.12.011
Abstract(304) PDF (207KB)(153)
Abstract:

Liver transplantation has been widely accepted as an effective treatment method for various types of irreversible acute and chronic liver diseases. After decades of steady and sustained development,liver transplantation techniques gradually become mature and stable. At present,all major transplantat...
Operation standards for adult living donor liver transplantation in China (version 2019)
Chinese Society of Organ Transplantation, Chinese Medical Association
2019, 35(12): 2703-2705. DOI: 10.3969/j.issn.1001-5256.2019.12.012
Abstract(450) PDF (281KB)(144)
Abstract:

The shortage of donor liver is a long-term problem for liver transplantation physicians in China,and in order to expand the source of donor liver,living donor liver transplantation has become one of the important options for patients with end-stage liver disease. In order to further standardize the ...
Chinese guidelines for the management of acute pancreatitis ( Shenyang , 2019 )
Pancreas Study Group, Chinese Society of Gastroenterology, Chinese Medical Association, Editorial Board of Chinese Journal of Pancreatology, Editorial Board of Chinese Journal of Digestion
2019, 35(12): 2706-2711. DOI: 10.3969/j.issn.1001-5256.2019.12.013
Abstract(7477) PDF (2153KB)(6467)
Abstract:

Acute pancreatitis is a common critical disease of the digestive system,and the update of relevant guidelines has important guiding significance in clinical practice. Based on the expert opinions in multiple disciplines,as well as clinical evidence at home and abroad in the past 5 years,this consens...
Guidelines for diagnosing and treating pediatric pancreaticobiliary maljunction
Subspecialty Group of Neonatal Surgery, Branch of Pediatric Surgery, Chinese Medical Association, Subspecialty Group of Pediatric Biliary Surgery, Branch of Pediatric Surgery, Chinese Medical Association
2019, 35(12): 2712-2715. DOI: 10.3969/j.issn.1001-5256.2019.12.014
Abstract(1209) PDF (1913KB)(356)
Abstract:
Original articles_Liver fibrosis and liver cirrhosis
Value of platelet count and gallbladder wall thickness in predicting esophageal varices in patients with liver cirrhosis
Duan ZhiHui, Zhou ShengYun, Li ZengKui, Zhai DongCai, Zhou KeRou, Sun XiaoFang, Wang YanHong, Wu YiJuan, Li SuRong, Wang JiTao
2019, 35(12): 2716-2720. DOI: 10.3969/j.issn.1001-5256.2019.12.015
Abstract(1483) PDF (1965KB)(277)
Abstract:
Objective To investigate the value of platelet count( PLT) and gallbladder wall thickness( GBWT) in predicting esophageal varices( EV) in patients with liver cirrhosis. Methods A retrospective analysis was performed for the clinical data of 100 patients who were diagnosed with hepatitis B cirrhosis ...
Original articles_Liver neoplasms
mRNA expression and significance of tumor necrosis factor-alpha-induced protein 8-like 2 and forkhead box P3 in peripheral blood mononuclear cells in patients with primary liver cancer
Kong Li, Zhang YuZhuo, Jin Meng, Wang ShanShan, Du JingHua, Zhang YuGuo, Wang RongQi, Ren WeiGuang, Nan YueMin
2019, 35(12): 2721-2724. DOI: 10.3969/j.issn.1001-5256.2019.12.016
Abstract(558) PDF (233KB)(77)
Abstract:
Objective To investigate the mRNA expression of tumor necrosis factor-alpha-induced protein 8-like 2( TIPE2) and forkhead box P3( Foxp3) of CD4+CD25+regulatory T cells( Tregs) in peripheral blood mononuclear cells( PBMCs) and their correlation in patients with primary liver cancer. Methods A total o...
Value of spleen stiffness and spleen volume in predicting posthepatectomy liver failure in patients with hepatocellular carcinoma
Chen Hao, Ma JunYong, Qian LiQiang, Yin GuoWen
2019, 35(12): 2725-2729. DOI: 10.3969/j.issn.1001-5256.2019.12.017
Abstract(1205) PDF (2045KB)(250)
Abstract:
Objective To investigate the value of spleen stiffness( SS) and spleen volume( SV) in predicting posthepatectomy liver failure( PHLF) in patients with hepatocellular carcinoma( HCC). Methods Related clinical data were collected from the patients with HCC who underwent hepatectomy in Suzhou Ninth Peo...
Expression of protein phosphatase 2A catalytic subunit in hepatoma cells after acute and chronic injury induced by hydrogen peroxide and aflatoxin B1 and its influence on hepatoma cells
Yang ChengLei, Huang Shen, Mo LaiMing, Tang Shen, Li XiYi, Zhang ZhiMing
2019, 35(12): 2730-2735. DOI: 10.3969/j.issn.1001-5256.2019.12.018
Abstract(1086) PDF (2567KB)(214)
Abstract:
Objective To investigate the expression of protein phosphatase 2 A catalytic subunit in hepatoma cells after acute and chronic injury induced by hydrogen peroxide and aflatoxin B1. Methods Hepatoma cells( HepG2/Huh-7 cells) were treated with different concentrations of hydrogen peroxide( 0,50,100,20...
Changes in the expression of 17-β-hydroxysteroid dehydrogenase 13 and mitofusin 2 in liver cancer tissue and a bioinformatics analysis
Ceng ChaiMing, Yan MaoLin, Shi YiHai, Guo TaiLin, Mei AiNong, Chen JianKang, Xu GuiPing, He XiaoHong
2019, 35(12): 2736-2740. DOI: 10.3969/j.issn.1001-5256.2019.12.019
Abstract(1316) PDF (2278KB)(223)
Abstract:
Objective To investigate the change in the expression of 17-β-hydroxysteroid dehydrogenase 13( HSD17 B13) and mitofusin2( MFN2) in hepatocellular carcinoma( HCC) tissue and its clinical significance,and to analyze target genes by bioinformatics methods.Methods Fifteen HCC patients who received surgi...
Original articles_Biliary diseases
Clinical effect of endoscopic ultrasonography in the diagnosis and evaluation of common bile duct stones
Cui YuFang, Bao JunJun, Song YuLin, Zhang Lei, Mei Qiao
2019, 35(12): 2741-2743. DOI: 10.3969/j.issn.1001-5256.2019.12.020
Abstract(1391) PDF (1874KB)(230)
Abstract:
Objective To investigate the value of endoscopic ultrasonography( EUS) in the diagnosis of common bile duct stones. Methods A total of 98 patients who attended The First Affiliated Hospital of Anhui Medical University from June 2017 to May 2019 and were suspected of common bile duct stones were enro...
Clinical value of ultra-thin electronic flexible endoscopy combined with intraluminal ultrasound in assisting percutaneous transhepatic biliary stricture biopsy
Jiao DeChao, Lei QinYu, Han XinWei, Li ZongMing, Bi YongHua, Zhang QuanHui
2019, 35(12): 2744-2747. DOI: 10.3969/j.issn.1001-5256.2019.12.021
Abstract(1601) PDF (2221KB)(252)
Abstract:
Objective To investigate the clinical value of Olympus ultra-thin electronic flexible endoscope BF-XP290 combined with the intraluminal ultrasound system in assisting percutaneous transhepatic biliary stricture biopsy. Methods From July to September,2018,12 patients with biliary obstruction underwen...
Clinicopathological features and prognosis of periampullary carcinomas in the pre-jaundice stage
Peng XiaoQian, Liu Lu, Jiao XiaoXiao, Zhou Lin
2019, 35(12): 2748-2753. DOI: 10.3969/j.issn.1001-5256.2019.12.022
Abstract(1264) PDF (1964KB)(223)
Abstract:
Objective To investigate the clinicopathological features and prognostic factors of periampullary carcinomas( PACs) in the pre-jaundice stage. Methods A retrospective analysis was performed for the clinical data of 518 patients with PACs who were admitted from January 2012 to December 2017,and accor...
Original articles_Others
Role and mechanism of action of endoplasmic reticulum stress in the formation of sex difference in liver diseases
Wang Jie, He YiHuai, Chen Huan, Long Jun, Xiao Xue
2019, 35(12): 2754-2758. DOI: 10.3969/j.issn.1001-5256.2019.12.023
Abstract(1235) PDF (2234KB)(226)
Abstract:

Objective To investigate the role and mechanism of endoplasmic reticulum stress in the formation of sex difference in liver diseases. Methods A retrospective analysis was performed to investigate the sex distribution of 23 043 patients with liver diseases in the outpatient service of hepatology and ...
Value of indocyanine green clearance test in predicting the short-term prognosis of patients with hepatitis B virus-related acute-on-chronic liver failure
Dou HongLian, He HongYan, Xiao CiJun, Wang Bo, Li Ye, Sheng YunJian, Deng CunLiang
2019, 35(12): 2759-2764. DOI: 10.3969/j.issn.1001-5256.2019.12.024
Abstract(1228) PDF (2018KB)(251)
Abstract:

Objective To investigate the value of indocyanine green( ICG) clearance test in evaluating the short-term prognosis of patients with hepatitis B virus( HBV)-related acute-on-chronic liver failure( HBV-ACLF),to establish a new model for prognostic evaluation based on indocyanine green retention rate ...
Clinical effect of Qingre Jiedu Liangxue prescription in treatment of mice with acute-on-chronic liver failure and related mechanism
Wang KaiXia, Zheng Chao, Zhang JingHao, Zhu XiaoJun, Wang Xuan, Kong XiaoNi, Gao YueQiu, Sun XueHua
2019, 35(12): 2765-2771. DOI: 10.3969/j.issn.1001-5256.2019.12.025
Abstract(1373) PDF (3849KB)(237)
Abstract:

Objective To investigate the mechanism of action of Qingre Jiedu Liangxue prescription in the treatment of mice with acute-on-chronic liver failure( ACLF). Methods A total of 36 male C57 BL/6 mice were randomly divided into normal group( n = 6),traditional Chinese medicine( TCM) group( n = 6),Wester...
Value of red blood cell distribution width,mean platelet volume,and neutrophil-lymphocyte ratio in the evaluation of primary biliary cholangitis
Yang Liu, Chen XiangJin, Li BianLi, Peng Ying, Xu LiHong
2019, 35(12): 2772-2775. DOI: 10.3969/j.issn.1001-5256.2019.12.026
Abstract(1425) PDF (1966KB)(244)
Abstract:

Objective To investigate the value of red blood cell distribution width( RDW),mean platelet volume( MPV),platelet distribution width( PDW),lymphocyte-monocyte ratio( LMR),platelet-lymphocyte ratio( PLR),and neutrophil-lymphocyte ratio( NLR)in evaluating the deterioration and progression of primary b...
Case reports
A case of hepatic neuroendocrine tumor with hepatic sinusoidal obstruction syndrome
Chen DongKui, Xu Yang
2019, 35(12): 2776-2777. DOI: 10.3969/j.issn.1001-5256.2019.12.027
Abstract(1065) PDF (1988KB)(252)
Abstract:
Hepatic sinusoidal obstruction syndrome induced by Chinese herb Emilia sonchifolia(L.) DC: A case report
Chen RuanQin, Zhuo HaiYan, Li XiaoLou, Chen Li
2019, 35(12): 2778-2779. DOI: 10.3969/j.issn.1001-5256.2019.12.028
Abstract(1093) PDF (1901KB)(226)
Abstract:
Liver injury induced by Dioscorea bulbifera,Swietenia macrophylla seeds,and Periploca forrestii: A report of 3 cases
Qi ChuanWang, Xian JianChun
2019, 35(12): 2780-2782. DOI: 10.3969/j.issn.1001-5256.2019.12.029
Abstract(1700) PDF (1872KB)(254)
Abstract:
Reviews
Role of hepatitis B virus-induced myeloid-derived suppressor cell subsets in chronic HBV infection
Wu ZhiHui, Yang MiaoMiao, Tu ZhengKun
2019, 35(12): 2783-2787. DOI: 10.3969/j.issn.1001-5256.2019.12.030
Abstract(905) PDF (1910KB)(216)
Abstract:
Hepatitis B virus( HBV) is a member of hepadnavirus,and HBV infection may not cause direct hepatocyte lesions. Host immune response determines whether the virus can be eliminated and is a major cause of HBV-related liver diseases. Myeloid-derived suppressor cells( MDSCs) are a group of non-lymphoid ...
Biological characteristics of high-mobility group box-1 and its role in the development,progression,and treatment of hepatitis B virus-related liver diseases
Yao ChuanXia, Wang MaoRong
2019, 35(12): 2788-2792. DOI: 10.3969/j.issn.1001-5256.2019.12.031
Abstract(958) PDF (1905KB)(209)
Abstract:
High-mobility group box-1( HMGB1) is a member of the high-mobility group proteins and is present in eukaryotic cells.HMGB1 is not only a nuclear protein but also a pro-inflammatory factor,and the increase in HMGB1 level in the body indicates cell destruction and inflammatory response. Hepatitis B vi...
Role of monocyte chemoattractant protein 1 and its receptor in the progression of liver fibrosis
Guo YueCheng, Lu LunGen
2019, 35(12): 2793-2795. DOI: 10.3969/j.issn.1001-5256.2019.12.032
Abstract(1105) PDF (1879KB)(230)
Abstract:
Liver fibrosis is a common reversible pathological change in chronic liver injury and may progress to liver cirrhosis,liver failure,and portal hypertension. In recent years,several studies have shown a significant change in chemokine profiles in patients with liver fibrosis,which is closely associat...
Noninvasive assessment of cirrhotic portal hypertension
Mu XueChun, Wang Yu, Ma Hong
2019, 35(12): 2796-2799. DOI: 10.3969/j.issn.1001-5256.2019.12.033
Abstract(1395) PDF (1902KB)(259)
Abstract:
Hepatic venous pressure gradient( HVPG) is the gold standard for the degree of cirrhotic portal hypertension and has limited use in clinical application,and therefore,there is an urgent need for noninvasive assessment methods for portal hypertension. This article introduces various serological,imagi...
Role and mechanism of berberine in treatment of hepatocellular carcinoma
Xu XiaoYang, Wang YuLu, Ping Jian, Zhao ZhangQing
2019, 35(12): 2800-2804. DOI: 10.3969/j.issn.1001-5256.2019.12.034
Abstract(1141) PDF (1908KB)(246)
Abstract:
A large number of studies have shown that berberine exerts an anti-tumor effect mainly by inhibiting cancer cell proliferation,inducing cancer cell death,inhibiting cancer cell metastasis and invasion,regulating the expression of endogenous oncogenes and tumor suppressor genes,affecting the activity...
Current status of associating liver partition and portal vein ligation for staged hepatectomy in treatment of liver metastasis of colorectal cancer
Liao Yang, Li ShengWei
2019, 35(12): 2805-2808. DOI: 10.3969/j.issn.1001-5256.2019.12.035
Abstract(1027) PDF (1891KB)(210)
Abstract:
At present,radical resection remains the best treatment strategy for liver metastasis of colorectal cancer,and patients with large or multiple tumors often face the problem of insufficient residual liver volume after hepatectomy,which may lead to serious complications including liver failure after s...
Role of hepatocyte mitophagy in the pathogenesis of nonalcoholic fatty liver disease
Zhou ZhenHua, Wang LingTai, Gao YueQiu
2019, 35(12): 2809-2811. DOI: 10.3969/j.issn.1001-5256.2019.12.036
Abstract(1260) PDF (1878KB)(264)
Abstract:
Nonalcoholic fatty liver disease has become the most important chronic liver disease in China and the leading cause of abnormal liver biochemical parameters in physical examination. Mitophagy can degrade the mitochondria with impaired function and misfolded protein in the liver to regulate cell deat...
Research advances in sodium-glucose co-transporter 2 inhibitor in treatment of type 2 diabetes mellitus with nonalcoholic fatty liver disease
Xue MiaoMiao, Li XuePing, Li Ya, Yan NaNa, Xu GangZhu, Song Mei
2019, 35(12): 2812-2816. DOI: 10.3969/j.issn.1001-5256.2019.12.037
Abstract(1378) PDF (1910KB)(223)
Abstract:
Nonalcoholic fatty liver disease( NAFLD) is a common complication of type 2 diabetes mellitus( T2 DM) and can progress to liver cirrhosis and even hepatocellular carcinoma,but there are still no effective pharmacotherapies for NAFLD at present. Sodium-glucose co-transporter 2 inhibitor( SGLT-2 i) is...
Research advances in antioxidants in the progression of alcoholic liver disease
Chen HaiZhen, Huang Jing
2019, 35(12): 2817-2819. DOI: 10.3969/j.issn.1001-5256.2019.12.038
Abstract(1218) PDF (1879KB)(237)
Abstract:
Alcoholic liver disease( ALD) is a series of chronic non-infectious liver diseases caused by long-term heavy alcohol consumption. Reactive oxygen species( ROS) is produced during alcohol metabolism,and if it is not eliminated completely,it may cause oxidative stress,which will further lead to inflam...
Clinical evaluation and prognosis prediction of drug-induced liver injury
Xing Lu, Wang Yu, Tao YanYan, Liu ChengHai
2019, 35(12): 2820-2823. DOI: 10.3969/j.issn.1001-5256.2019.12.039
Abstract(1406) PDF (1890KB)(311)
Abstract:
Drug-induced liver injury( DILI) is commonly seen in clinical practice and may bring serious harm to health. It is an important reason for the failure of liver disease treatment and new drug research and development. The clinical diagnosis of DILI remains a difficult issue in the world,and therefore...
Research advances in hepatic encephalopathy after transjugular intrahepatic portosystemic shunt
Wang Zhong, Liu FuQuan
2019, 35(12): 2824-2827. DOI: 10.3969/j.issn.1001-5256.2019.12.040
Abstract(1268) PDF (1888KB)(247)
Abstract:
Transjugular intrahepatic portosystemic shunt( TIPS) has become an effective method for the treatment of portal hypertension.Although the use of polytetrafluoroethylene covered stents enhances shunt patency,hepatic encephalopathy remains a significant issue after TIPS. This article reviews the epide...
Effect of endoplasmic reticulum stress and autophagy on hepatocyte apoptosis
Gong Jing, Jie XinKe
2019, 35(12): 2828-2832. DOI: 10.3969/j.issn.1001-5256.2019.12.041
Abstract(1413) PDF (1903KB)(267)
Abstract:
Endoplasmic reticulum stress and autophagy are two two-edged swords. On the one hand,in case of intracellular environment disturbance,unfolded protein response reduces protein synthesis,promotes protein degradation,and increases protein folding to restore intracellular homeostasis through three sign...
Endoscopic therapy for acute suppurative cholangitis with common bile duct stones
Tian Wen, Zhou ZhongYin
2019, 35(12): 2833-2836. DOI: 10.3969/j.issn.1001-5256.2019.12.042
Abstract(1342) PDF (1889KB)(244)
Abstract:
Acute suppurative cholangitis( ASC) is an acute infectious disease of the biliary tract caused by bacterial infection and biliary obstruction. Common bile duct stone is the most common cause of biliary obstruction. Due to the characteristics of rapid onset,rapid progress,various complications,and hi...
Immunotherapy for biliary tract cancer: Current status and perspectives
Luo Kui, Sun Hang, Wu ChuanXin
2019, 35(12): 2837-2840. DOI: 10.3969/j.issn.1001-5256.2019.12.043
Abstract(1433) PDF (1886KB)(263)
Abstract:
Biliary tract cancer( BTC) is rare in clinical practice and is difficult to diagnose in the early stage,and conventional treatment methods have unsatisfactory clinical effects. As a new research hotspot at present,immunotherapy has been proven to have a promising future in the treatment of a variety...
Conference overviews
Minutes of annual meeting of APALD Tianjin alliance (2019)
Zhang Qing, Li Hai
2019, 35(12): 2841-2842. DOI: 10.3969/j.issn.1001-5256.2019.12.044
Abstract(737) PDF (2058KB)(200)
Abstract:
    

The first journal specializing in hepatobiliary and pancreatic diseases in China

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Sponsor：Jilin University

Academic Support: Chinese Society of Hepatology，Chinese Medical Association

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