Diagnostic value of serum lipase combined with Ranson or BISAP scoring system in assessment of severity of acute pancreatitis

Chen DongLai; Liao ZhenHai; Lin ShunQuan

doi:10.3969/j.issn.1001-5256.2016.02.026

Issue 2

Feb. 2016

Turn off MathJax

Article Contents

Abstract

References

Article Navigation > Journal of Clinical Hepatology > 2016 > 32(2): 324-328

PDF( 1562 KB)

Diagnostic value of serum lipase combined with Ranson or BISAP scoring system in assessment of severity of acute pancreatitis

DOI: 10.3969/j.issn.1001-5256.2016.02.026

Department of Internal Medicine,The Second People' s Hospital of Huidong County

Received Date: 2015-07-20
Published Date: 2016-02-20

Abstract

Abstract

Objective To investigate the diagnostic value of serum lipase combined with the Ranson or BISAP scoring system in the assessment of severity of acute pancreatitis. Methods A total of 314 patients with acute pancreatitis who were admitted to The Second People' s Hospital of Huidong County from February 2012 to February 2015 were selected and divided into mild acute acute pancreatitis( MAP) group( 202 patients) and severe acute pancreatitis( SAP) group( 112 patients). Serum lipase determination,Ranson scoring,BISAP scoring,serum lipase determination combined with Ranson scoring,and serum lipase determination combined with BISAP scoring were performed for all the patients. The t- test was applied for comparison of continuous data between groups,the chi- square test was applied for comparison of categorical data between groups,and the Z test was applied for the comparison of area under the receiver operating characteristic curve( AUC) and Youden index between different methods. Results The patients with SAP had significantly higher serum lipase level,Ranson score,and BISAP score than those with MAP( t = 14. 89,11. 89,and 5. 12,P = 0. 003,0. 007,and 0. 037). As for the AUCs for the prediction of organ failure,pancreatic necrosis,and death,serum lipase determination combined with the BISAP scoring system had significantly higher AUCs than the BISAP scoring system( Z = 7. 54,7. 11,and 7. 57,P = 0. 033,0. 031,and 0. 030),serum lipase determination combined with the Ranson scoring system had significantly higher AUCs than the Ranson scoring system( Z = 5. 23,5. 78,and 6. 18,P =0. 037,0. 034,and 0. 032),and serum lipase determination combined with the BISAP scoring system had significantly higher AUCs than serum lipase determination combined with the Ranson scoring system( Z = 13. 55,8. 33,and 7. 66,P = 0. 005,0. 029,and 0. 031). As for Youden index for the prediction of organ failure,pancreatic necrosis,and death,serum lipase determination combined with the Ranson scoring system had a significantly higher Youden index than the Ranson scoring system( Z = 5. 17,6. 89,and 7. 35,P = 0. 038,0. 032,and 0. 027),serum lipase determination combined with the BISAP scoring system had a significantly higher Youden index than the BISAP scoring system( Z = 7. 54,7. 22,and 9. 57,P = 0. 030,0. 031,and 0. 025),and serum lipase determination combined with the BISAP scoring system had a significantly higher Youden index than serum lipase determination combined with the Ranson scoring system( Z =10. 11,10. 23,and 13. 24,P = 0. 020,0. 019,and 0. 010). Conclusion Compared with the Ranson scoring system or BISAP scoring system alone,serum lipase determination combined with the Ranson or BISAP scoring system is more accurate in the assessment of severity of acute pancreatitis,and serum lipase determination combined with the BISAP scoring system has a higher sensitivity and a greater diagnostic value in clinical practice.
- pancreatitis,
- lipase,
- Ranson scoring system,
- BISAP scoring system,
- diagnosis

FullText(HTML)

References(16)

References

[1] BANKS PA,FREEMAN ML,Practice Parameters Committee of the American College of Gastroenterology.Practice guidelines in acutepancreatitis[J].Am J Gastroenterol,2006,101(10):2379-2400.

[2]ZHOU HH,LIN LJ,ZHENG CQ,et al.Significance of BISAP combined with coagulation parameters in predicting the severity of acute pancreatitis[J].World Chin J Dig,2012,20(18):1638-1643.(in Chinese)周慧慧,林连捷,郑长青,等.BISAP联合凝血指标对急性胰腺炎严重程度评估的意义[J].世界华人消化杂志,2012,20(18):1638-1643.

[3]ZHANG J,ZHAO T,CAO RG,et al.Comparison among BISAP,APACHEⅡand Ranson's scoring system in predicting severity of acute pancreatitis[J].Chin J Gen Surg,2014,23(9):1176-1181.(in Chinese)张嘉,赵涛,曹荣格,等.BISAP、APACHEⅡ和Ranson评分在预测急性胰腺炎严重程度的比较[J].中国普通外科杂志,2014,23(9):1176-1181.

[4]BOLLEN TL,SINGH VK,MAURER R,et al.A comparative evaluation of radiologic and clinical scoring systems in the early prediction of severity in acute pancreatitis[J].Am J Gastroenterol,2012,107(4):612-619.

[5]MAO PF,TANG W.Clinical value of BISAP scoring system in predicting severity of acute pancreatitis[J/CD].Chin J Clinicians:Electronic Edition,2013,7(11):5129-5131.(in Chinese)冒朋飞,唐文.BISAP评分系统预测急性胰腺炎严重程度的临床应用价值[J/CD].中华临床医师杂志:电子版,2013,7(11):5129-5131.

[6]DAMBRAUSKAS Z,GULBINAS A,PUNDZIUS J,et al.Value of the different prognostic systems and biological markers for predicting severity and progression of acute pancreatitis[J].Scand J Gastroenterol,2010,45(7-8):959-970.

[7]ZHOU YY,YANG L,LIAO ZL,et al.BISAP score vs Ranson's criteria in predicting outcomes of acute pancreatitis[J].J Third Milit Med Univ,2012,34(7):658-661.(in Chinese)周圆圆,杨丽,廖忠莉,等.BISAP与Ranson's评分对急性胰腺炎患者预后评估的比较[J].第三军医大学学报,2012,34(7):658-661.

[8]HUANG L,XU P,SHI XF,et al.The role of three criteria in assessment of severity and prognosis of acute pancreatitis[J].Chin J Dig,2012,32(6):400-403.(in Chinese)黄玲,徐萍,史先芳,等.三种评分标准对急性胰腺炎病情和预后的评估作用[J].中华消化杂志,2012,32(6):400-403.

[9]YANG J,HUANG Q,LIN XS,et al.Value of serum amylase and lipase in early diagnosis of acute pancreatitis:a Meta-analysis[J].World Chin J Dig,2012,22(8):1171-1178.(in Chinese)杨骥,黄强,林先盛,等.血清脂肪酶和淀粉酶在早期急性胰腺炎中诊断价值的Meta分析[J].世界华人消化杂志,2012,22(8):1171-1178.

[10]CHEN JF.Research advances in medical treatment of acute pancreatitis[J].Chin J Geriatr Care,2014,12(1):79-80.(in Chinese)陈剑锋.急性胰腺炎内科治疗的研究进展[J].中国老年保健医学,2014,12(1):79-80.

[11]FAN JY,XU JY.Prognostic values of Ranson scoring,APACHE II scoring,and CT scoring for secondary infection in patients with severe acute pancreatitis[J/CD].Chin J Clinicians:Electronic Edition,2013,7(17):8011-8013.(in Chinese)樊景云,徐建玉.Ranson评分、APACHEⅡ评分和CT评分对重症急性胰腺炎患者继发感染的预后价值[J/CD].中华临床医师杂志:电子版,2013,7(17):8011-8013.

[12]WANG DX,LIN LJ,LIN Y,et al.Clinical value of bedside index for severity in acute pancreatitis scoring system to predicting severity and prognosis of acute pancreatitis[J].J Chin Practical Diagn and Ther,2014,28(7):672-675.(in Chinese)王东旭,林连捷,林艳,等.急性胰腺炎床边指数评分对疾病程度及预后的预测价值[J].中华实用诊断与治疗杂志,2014,28(7):672-675.

[13]HUANG YL,ZHANG M,MA LN.Value of bedside index for severity in acute pancreatitis scoring system in early severity assessment of acute pancreatitis[J/CD].Chin J Clinicians:Electronic Edition,2011,6(17):5090-5092.(in Chinese)黄玉莲,张玫,马丽娜.急性胰腺炎严重程度床边指数评分对急性胰腺炎严重程度的早期评估价值[J/CD].中华临床医师杂志:电子版,2011,6(17):5090-5092.

[14]XIE SG,HU YQ,RAO H,et al.Study on the role of amylase,lipase and C-reactive protein in the diagnosis of acute pancreatitis[J].Chin J Health Lab Technol,2014,34(20):2946-2948.(in Chinese)谢圣高,胡玉倩,饶绘,等.淀粉酶、脂肪酶和C-反应蛋白检测对急性胰腺炎的诊断意义[J].中国卫生检验杂志,2014,34(20):2946-2948.

[15]WANG YH,GAN L,WANG M,et al.Observation of efficacy of venous hemofiltration in treatment of 36 patients with severe acute pancreatitis[J].Chin J Nosocomiol,2013,23(2):313-314,317.王玉辉,甘玲,王淼,等.静脉血液滤过治疗36例重症急性胰腺炎疗效观察[J].中华医院感染学杂志,2013,23(2):313-314,317.(in Chinese)

[16]HAN L,LAI YD,ZENG QZ.BISAP score vs Ranson criteria in predicting the severity and prognosis of patients with acute pancreatitis[J].China Prac Med,2013,8(34):1-2.(in Chinese)韩琳,赖亚栋,曾群章.BISAP评分与Ranson评分对急性胰腺炎病情及预后评估的比较[J].中国实用医药,2013,8(34):1-2.

Relative Articles

[1]	Xiaoqing WANG, Jie LONG, Fei WANG, Zhexiong LIAN. Impact of cancer-associated fibroblasts on immunotherapy and liver metastasis in colorectal cancer[J]. Journal of Clinical Hepatology, 2024, 40(6): 1183-1190. doi: 10.12449/JCH240618
[2]	Rui ZHANG, Jinhong CHEN. Treatment strategy of non-radical surgical resection for colorectal cancer liver metastases[J]. Journal of Clinical Hepatology, 2024, 40(7): 1295-1300. doi: 10.12449/JCH240702
[3]	Chinese College of Surgeons, Chinese Medical Doctor Association, Chinese Society Gastrointestinal Surgery, Chinese Society of Surgery, Chinese Medical Association, Chinese Society of Colorectal Surgery, Chinese Society of Surgery, Chinese Medical Association, Section of Colorectal Oncology, Chinese Society of Oncology, Chinese Medical Association, Colorectal Cancer Professional Committee, Chinese Anti-Cancer Association, Colorectal Cancer Professional Committee, Chinese Medical Doctor Association, Colorectal Cancer Expert Committee, Chinese Society of Clinical Oncology, Chinese College of Colorectal Surgeons, Chinese College of Surgeons, Chinese Medical Doctor Association, Metastasis Research Committee, Anorectal Branch of Chinese Medical Doctor Association, Colorectal Liver Metastases Professional Committee, China International Exchange and Promotive Association for Medical and Health Care. China guideline for diagnosis and comprehensive treatment of colorectal liver metastases (2020 edition)[J]. Journal of Clinical Hepatology, 2021, 37(3): 543-553. doi: 10.3969/j.issn.1001-5256.2021.03.009
[4]	Xuemin LI, Hao WANG, Junjie WANG. Stereotactic ablative radiotherapy for colorectal cancer liver metastasis[J]. Journal of Clinical Hepatology, 2021, 37(3): 522-526. doi: 10.3969/j.issn.1001-5256.2021.03.006
[5]	Xiangqian HUANG, Xiaomeng YAN, Mingda ZHANG, Jing WU, Jianhong CHEN. Association between nonalcoholic fatty liver disease and colorectal neoplasms[J]. Journal of Clinical Hepatology, 2021, 37(12): 2947-2950. doi: 10.3969/j.issn.1001-5256.2021.12.045
[6]	Gao BenJian, Luo Jia, Liu Ying, Yang XiaoLi, Su Song, Li Bo. Efficacy and safety of laparoscopic versus open liver resection in treatment of colorectal cancer liver metastasis: A Meta-analysis[J]. Journal of Clinical Hepatology, 2020, 36(3): 573-579. doi: 10.3969/j.issn.1001-5256.2020.03.021
[7]	Li Jiang, Hou Yu, Cai XiaoBei, Xu ChengLei, Yi GenFa. Clinical effect of local treatment based on limited segmental resection in improving the prognosis of liver oligometastasis after surgery for colorectal cancer[J]. Journal of Clinical Hepatology, 2020, 36(8): 1763-1767. doi: 10.3969/j.issn.1001-5256.2020.08.017
[8]	Liao Yang, Li ShengWei. Current status of associating liver partition and portal vein ligation for staged hepatectomy in treatment of liver metastasis of colorectal cancer[J]. Journal of Clinical Hepatology, 2019, 35(12): 2805-2808. doi: 10.3969/j.issn.1001-5256.2019.12.035
[9]	Liu SiFu, Xie ZhengYuan. Association between nonalcoholic fatty liver disease and colorectal tumors[J]. Journal of Clinical Hepatology, 2019, 35(9): 2091-2094. doi: 10.3969/j.issn.1001-5256.2019.09.046
[10]	Min YongFeng, Zhang Bo. Microwave ablation combined with 125I particle implantation in treatment of hepatic metastasis with diaphragm perforation: A case report[J]. Journal of Clinical Hepatology, 2018, 34(8): 1758-1759. doi: 10.3969/j.issn.1001-5256.2018.08.034
[11]	Li Hao, Duan XuHua, Han XinWei, Ren JianZhuang, Li FengYao, Kuang DongLin, Li FangZheng. Clinical effect of transarterial chemoembolization combined with radiofrequency ablation in treatment of rabbit VX2 liver tumors[J]. Journal of Clinical Hepatology, 2018, 34(4): 779-783. doi: 10.3969/j.issn.1001-5256.2018.04.017
[12]	Sun Wei, Ding XiaoYan, Chen JingLong, Li WenDong, Guo XiaoDi, Shen YanJun, Sun ShaSha, Teng Ying, Liu XiaoMin, Wei JianYing. Clinical effect and safety of radiofrequency ablation combined with systemic chemotherapy in treatment of unresectable or postoperative recurrent intrahepatic cholangiocellular carcinoma[J]. Journal of Clinical Hepatology, 2018, 34(8): 1717-1722. doi: 10.3969/j.issn.1001-5256.2018.08.025
[13]	Society for Minimally Invasive Surgery, Chinese Research Hospital Association. Technical guidelines for simultaneous laparoscopic and robotic resection of colorectal cancer with liver metastasis ( Revised in 2017)[J]. Journal of Clinical Hepatology, 2018, 34(3): 494-497. doi: 10.3969/j.issn.1001-5256.2018.03.007
[14]	An DongJun, An Lin, Zhang Cheng, Zhao WeiAn, Han Li. Efficacy of laparoscopic microwave ablation in treatment of malignant liver tumors[J]. Journal of Clinical Hepatology, 2017, 33(11): 2158-2161. doi: 10.3969/j.issn.1001-5256.2017.11.021
[15]	Song Li, Zou YingHua. Prevention and treatment of complications after radiofrequency ablation for hepatic tumors in high-risk locations[J]. Journal of Clinical Hepatology, 2017, 33(4): 647-650. doi: 10.3969/j.issn.1001-5256.2017.04.009
[16]	Lu NingNing, Sun Bin, Cui XiongWei, Long Jiang, Gao WenFeng, Zheng JiaSheng. Diagnosis and treatment of subcapsular hemorrhage after liver tumor ablation[J]. Journal of Clinical Hepatology, 2017, 33(12): 2326-2330. doi: 10.3969/j.issn.1001-5256.2017.12.014
[17]	Wang DongXu, Huo TingTing, Tian YaoWen, Zhao Lei. Current status of research on microRNA associated with colorectal cancer liver metastasis[J]. Journal of Clinical Hepatology, 2016, 32(12): 2387-2390. doi: 10.3969/j.issn.1001-5256.2016.12.034
[18]	Jian QianHong, Zheng FangRong, Yan Xiong. Current status of research on transcatheter arterial chemoembolization in treatment of colorectal cancer liver metastasis[J]. Journal of Clinical Hepatology, 2016, 32(6): 1216-1219. doi: 10.3969/j.issn.1001-5256.2016.06.047
[19]	Wang Xin, Zhang Hui, He XiaoJun, Li XinHui, Liu Yang, Zhang HongYi. Clinical effect of precise sequential interventional therapy in patients with unresectable hepatic metastasis after surgery for colorectal cancer[J]. Journal of Clinical Hepatology, 2016, 32(3): 518-521. doi: 10.3969/j.issn.1001-5256.2016.03.025
[20]	Zhang ZhiQuan. Analysis of prognostic factors for patients treated by radical resection of liver metastases from colorectal cancer[J]. Journal of Clinical Hepatology, 2015, 31(9): 1455-1457. doi: 10.3969/j.issn.1001-5256.2015.09.022

Supplements(0)

Cited By

Cited by

Periodical cited type(2)

1.	凌清儿，张戎. 肝纤维化治疗的研究进展. 现代医药卫生. 2023(11): 1926-1931 .
2.	揭阳，叶林茂，何怡，邵畅，孙希光，张俊杰. 基于IFN-γ/STAT1/Smad7通路探讨疏肝健脾活血方抗肝纤维化作用机制. 中华中医药杂志. 2023(09): 4136-4141 .

Other cited types(3)

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views (2709) PDF downloads(427)

Diagnostic value of serum lipase combined with Ranson or BISAP scoring system in assessment of severity of acute pancreatitis

DOI: 10.3969/j.issn.1001-5256.2016.02.026