血清拟胆碱酯酶活性与肝硬化Child-Pugh分级关系的研究

To study the relationship between the activity of serum pseudocholinesterase (PChE) and Child-Pugh classification in hepatic cirrhosis, 64 serum samples of patients with hepatic cirrhosis and 50 serum samples of the healthy were detected for hepatic functional indexes: serum albumin, total bilirubin and PChE, and the patients classified according to the Child-Pugh score were included in the study. The results showed that the activity of PChE remarkablely declined in hepatic cirrhotic patients. According to the Child-Pugh classification, the PChE in different groups varied obviously. Therefore, the activity of PChE in serum can be regarded as an effective marker to the extent of hepatic cirrhosis, which has the important guiding value on diagnosis and prognostic evaluation of hepatic cirrhosis.