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Volume 38 Issue 1
Jan.  2022
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Article Navigation >  Journal of Clinical Hepatology  > 2022  >  38(1): 201-205

Research advances in in vitro models for nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2022.01.035

  • Department of Gastroenterology, The Affiliated Hospital of Yanbian University, Yanji, Jilin 133000, China

Research funding:

National Natural Science Foundation of China (81860110)

  • Received Date: 2021-05-19
  • Accepted Date: 2021-06-03
  • Published Date: 2022-01-20
    Abstract
  • The incidence rate of nonalcoholic fatty liver disease (NAFLD) is increasing year by year, with limited treatment methods, and its pathogenesis is a research hotspot at present. In order to better clarify its pathogenesis, it is urgent to develop advanced, safe, and effective in vitro or in vivo models to understand and develop treatment strategies for this disease. This article reviews the in vitro models commonly used in the preclinical study of NAFLD and discusses their advantages and disadvantages, so as to provide a theoretical basis for the pathogenesis and treatment of NAFLD.

     

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