2022 No. 9

2022 No.9

Theme Issue: Integrated Traditional Chinese and Western Medicine Therapy for Liver Cirrhosis and Its Main Comorbidities

Executive Chief Editor: LIU Ping

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

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Editorial

Research advances in integrated traditional Chinese and Western medicine therapy for liver cirrhosis

Shili JIANG, Ping LIU

2022, 38(9): 1953-1955. DOI: 10.3969/j.issn.1001-5256.2022.09.001

Abstract(1212)

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Abstract:
The combination of traditional Chinese medicine and Western medicine is an important approach to improve the treatment outcome of liver cirrhosis. Long-term diagnosis and treatment practice and clinical studies of the prevention and treatment of chronic hepatitis B cirrhosis have shown that antivira...

Discussions by Experts

Integrated traditional Chinese and Western medicine diagnosis and treatment of cirrhotic ascites

Lei WANG

2022, 38(9): 1956-1961. DOI: 10.3969/j.issn.1001-5256.2022.09.002

Abstract(1165)

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Ascites is the most common complication of decompensated liver cirrhosis. Recurrent massive ascites seriously affects the quality of life and prognosis of patients, and therefore, effective control of ascites is an important link in the treatment of liver cirrhosis. Based on the clinical reports in ...

Advances in the integrated traditional Chinese and Western medicine diagnosis and treatment of gastroesophageal variceal bleeding due to liver cirrhosis

Yongping MU

2022, 38(9): 1962-1968. DOI: 10.3969/j.issn.1001-5256.2022.09.003

Abstract(1161)

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Portal hypertension is not only the outcome of liver cirrhosis, but also the main cause of gastroesophageal varices, and variceal bleeding may lead to dangerous conditions and even endanger the life of patients. Therefore, standardization of endoscopic screening, prevention of first-time bleeding, e...

Integrated traditional Chinese and Western medicine diagnosis and treatment of hepatic encephalopathy: Advances and perspectives

Xianbo WANG, Ke SHI

2022, 38(9): 1969-1973. DOI: 10.3969/j.issn.1001-5256.2022.09.004

Abstract(1215)

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Hepatic encephalopathy is the most common complication of liver cirrhosis and portal hypertension, and a confirmed diagnosis requires the clarification of predisposing factors and disease stage based on neuropsychological tests or clinical symptoms and signs. The treatment of hepatic encephalopathy ...

Integrated traditional Chinese and Western medicine diagnosis and treatment of hepatorenal syndrome

Jiaqi LIANG, Wen LIU

2022, 38(9): 1974-1979. DOI: 10.3969/j.issn.1001-5256.2022.09.005

Abstract(968)

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Abstract:
As a common complication of end-stage liver disease, hepatorenal syndrome (HRS) is functional acute renal failure that occurs on the basis of severe liver diseases and is a group of clinical syndromes characterized by renal insufficiency, abnormal endogenous vascular substances, and hemodynamic chan...

Integrated traditional Chinese and Western medicine diagnosis and treatment of liver cirrhosis with diabetes

Changqing ZHAO

2022, 38(9): 1980-1985. DOI: 10.3969/j.issn.1001-5256.2022.09.006

Abstract(785)

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Abstract:
Hepatogenous diabetes (HD) is a common complication of liver cirrhosis and can reduce survival rate and increase the risk of other complications. It differs from type 2 diabetes in terms of etiology, pathogenesis, and diagnostic methods. There are currently no guidelines for HD treatment in China an...

Guidelines

Expert consensus for clinical application of Wuling capsule(pill) in the treatment of chronic hepatitis B

Branch of Hepatobiliary Diseases, Chinese Association of Chinese Medicine

2022, 38(9): 1986-1989. DOI: 10.3969/j.issn.1001-5256.2022.09.007

Abstract(1163)

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Chinese medicine practice guide for acupoint catgut embedding in treating non-alcoholic fatty liver disease

Branch of Hepatobiliary Diseases, Chinese Association of Chinese Medicine

2022, 38(9): 1990-1993. DOI: 10.3969/j.issn.1001-5256.2022.09.008

Abstract(894)

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Recommendations for EASL clinical practice guidelines on sclerosing cholangitis (2022)

Changcun GUO, Ying HAN

2022, 38(9): 1994-1996. DOI: 10.3969/j.issn.1001-5256.2022.09.009

Abstract(578)

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Recommendations for EASL clinical practice guidelines on the management of hepatic encephalopathy (2022)

Huimin LIU, Yuan HUANG

2022, 38(9): 1997-1998. DOI: 10.3969/j.issn.1001-5256.2022.09.010

Abstract(1007)

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An excerpt of the EASL clinical practice guidelines on haemochromatosis

Kunyan HAO, Yong WANG, Yuecheng YU

2022, 38(9): 1999-2004. DOI: 10.3969/j.issn.1001-5256.2022.09.011

Abstract(1006)

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Abstract:
In March 2022, EASL released a new version of the clinical practice guidelines on haemochromatosis. Haemochromatosis is characterized by elevated transferrin saturation (TSAT) and progressive iron overload mainly involving the liver, and early diagnosis and venesection can prevent liver cirrhosis, h...

Original Articles_Viral Hepatitis

Influencing factors for liver inflammation and fibrosis in the immune-tolerant phase of HBV infection

Chunyun LIU, Lixian CHANG, Junyi LI, Yanwei QI, Weikun LI, Huimin LI, Yingyuan ZHANG, Jianpeng GAO, Li LIU

2022, 38(9): 2005-2009. DOI: 10.3969/j.issn.1001-5256.2022.09.012

Abstract(598)

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Objective To evaluate the degree of liver injury and liver fibrosis in patients in the immune-tolerant phase of chronic HBV infection, and to provide a basis for judging the condition of patients in the immune-tolerant phase. Methods A total of 300 patients with HBV DNA ≥10⁷ IU/mL, alanine aminotran...

Original Articles_Fatty Liver Diseases

Influence of histone deacetylase 1 on insulin resistance in a cell model of nonalcoholic fatty liver disease

Heng ZHU, Weizong KONG, Guiqun HUANG, Yu BAI, Yingchun WANG

2022, 38(9): 2010-2015. DOI: 10.3969/j.issn.1001-5256.2022.09.013

Abstract(621)

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Abstract:
Objective To investigate the promoting effect of histone deacetylase 1 (HDAC1) expression on insulin resistance (IR) in nonalcoholic fatty liver disease (NAFLD) cells by establishing an HepG2 cell model of high fat-induced NAFLD. Methods HepG2 cells were divided into control group, model group (OA),...

Effect of Huatan Qushi Huoxue prescription on lipopolysaccharide-induced pyroptosis of macrophages

Minghao LIU, Sutong LIU, Dongfang SHANG, Lihui ZHANG, Yajiao GU, Wenxia ZHAO

2022, 38(9): 2016-2019. DOI: 10.3969/j.issn.1001-5256.2022.09.014

Abstract(975)

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Abstract:
Objective To investigate the effect of Huatan Qushi Huoxue prescription on lipopolysaccharide (LPS)-induced pyroptosis of RAW264.7 cells and its mechanism. Methods An in vitro cell model of LPS-induced activated RAW264.7 was established and divided into blank group, model group, high-, middle-, and ...

Original Articles_Liver Fibrosis and Liver Cirrhosis

Effect of Ganshuang granule combined with entecavir on portal vein thrombosis in patients with hepatitis B cirrhosis

Li LIU, Junyi LI, Chunyun LIU, Lixian CHANG, Lihua ZHANG, Hongli HUANG, Yu LUO, Jianpeng GAO

2022, 38(9): 2020-2026. DOI: 10.3969/j.issn.1001-5256.2022.09.015

Abstract(959)

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Abstract:
Objective To investigate the effect of Ganshuang granule combined with entecavir on portal vein thrombosis (PVT) in patients with hepatitis B cirrhosis. Methods A total of 356 patients with hepatitis B cirrhosis who attended and were hospitalized in The Third People's Hospital of Kunming from Januar...

The role of integrin α4 in the anti-liver fibrosis effect of the sticky sugar amino acid extract of Periplaneta americana

Jie LU, Yixia ZHOU, Ye LIU, Ya GAO, Kexuan CHEN, Dingchun LI, Yihui CHEN, Huaie LIU, Hongtu WANG, Wu LI

2022, 38(9): 2027-2033. DOI: 10.3969/j.issn.1001-5256.2022.09.016

Abstract(685)

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Objective To investigate the mechanism of action of integrin α4 (ITGA4) in liver fibrosis based on the anti-liver fibrosis effect of sticky sugar amino acid (SSAA) in rats. Methods A rat model of liver fibrosis was induced by intraperitoneal injection of CCl₄, and then colchicine and low-, middle-, ...

Effect of metformin on liver fibrosis in a mouse model of Budd-Chiari syndrome

Jing YANG, Suxin LI, Yuehui ZHANG, Luhao LI, Zhaochen LIU, Dongqi SHEN, Xiaowei DANG

2022, 38(9): 2034-2039. DOI: 10.3969/j.issn.1001-5256.2022.09.017

Abstract(984)

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Abstract:
Objective To investigate the effect of metformin on liver fibrosis in a mouse model of Budd-Chiari syndrome and its mechanism. Methods A total of 30 male C57 mice were randomly divided into sham-operation group (SHAM group) with 6 mice, sham operation+ metformin group (SHAM+M group) with 5 mice, Bud...

Effect of Yangxue Rougan pills on the TGF-β1/Smad signaling pathway in a rat model of liver fibrosis induced by multiple factors

Yan CHAI, Tao ZHANG, Yinke FAN, Aiwu HUI, Lintao ZHAO, Fang LI, Xiaoli ZHANG

2022, 38(9): 2040-2045. DOI: 10.3969/j.issn.1001-5256.2022.09.018

Abstract(682)

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Abstract:
Objective To investigate the effect of Yangxue Rougan pills on a rat model of liver fibrosis induced by multiple factors and the mechanism of action of Yangxue Rougan pills in the treatment of liver fibrosis. Methods A total of 50 male rats were randomly divided into blank control group, multi-facto...

Original Articles_Liver Neoplasms

Application of the three-dimensional visualization ablation planning system in radiofrequency ablation for hepatocellular carcinoma

Rong HE, Zhe JIA, Li JIANG, Ke ZHANG

2022, 38(9): 2046-2052. DOI: 10.3969/j.issn.1001-5256.2022.09.019

Abstract(515)

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Abstract:
Objective To investigate the significance of the three-dimensional visualization ablation planning system in radiofrequency ablation for liver cancer. Methods A total of 71 patients who received radiofrequency ablation for hepatocellular carcinoma in Beijing Ditan Hospital, Capital Medical Universit...

Clinical effect of transcatheter arterial chemoembolization combined with microwave ablation versus repeat resection in treatment of recurrent hepatocellular carcinoma

Jun LING, Wenwu WAN, Zheng ZENG, Huihua YAO, Ou JIANG, Bing DING

2022, 38(9): 2053-2060. DOI: 10.3969/j.issn.1001-5256.2022.09.020

Abstract(565)

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Abstract:
Objective To investigate the clinical effect of transcatheter arterial chemoembolization (TACE) combined with microwave ablation (MWA) (TACE-MWA) versus repeat resection (RR) in the treatment of recurrent hepatocellular carcinoma (RHCC). Methods A total of 178 patients with RHCC who were admitted to...

Prognostic value of several immune and inflammatory indices after curative-intent resection for intrahepatic cholangiocarcinoma

Bingqi MA, Huijuan MENG, Wei ZHANG, Xiaofeng DONG, Meng WANG, Jie DOU, Yuning WU, Shiping LI

2022, 38(9): 2061-2066. DOI: 10.3969/j.issn.1001-5256.2022.09.021

Abstract(529)

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Abstract:
Objective To investigate the value of different immune and inflammatory indices in predicting the survival outcome of patients with intrahepatic cholangiocarcinoma (ICC) after curative-intent resection. Methods A retrospective analysis was performed for the case data of 122 patients with ICC who und...

Original Articles_Other Liver Diseases

Clinical features of drug-induced liver injury due to Tripterygium wilfordii preparation and concomitant medications in patients with rheumatoid arthritis

Tingting SHEN, Guangyao LI, Qiong LUO, Meng LI, Xin SUN, Yanyan TAO, Zushan ZHOU, Chenghai LIU

2022, 38(9): 2067-2072. DOI: 10.3969/j.issn.1001-5256.2022.09.022

Abstract(762)

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Abstract:
Objective To investigate the clinical features of drug-induced liver injury (DILI) due to Tripterygium wilfordii preparation and concomitant medications in patients with rheumatoid arthritis (RA). Methods A retrospective analysis was performed for the clinical data of 112 RA patients with DILI cause...

Features of liver function in pediatric patients infected with Delta variant versus Omicron variant of severe acute respiratory syndrome coronavirus 2

Ye ZHAO, Jialong GUAN, Yuzhen MAI, Haohui DENG

2022, 38(9): 2073-2077. DOI: 10.3969/j.issn.1001-5256.2022.09.023

Abstract(558)

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Abstract:
Objective To summarize and analyze the features of liver function in pediatric patients infected with Delta variant versus Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Methods In this study, an analysis was performed for the liver function test results of the loca...

Influencing factors for hypotension in patients undergoing double plasma molecular adsorption system artificial liver support therapy

Dongyan HU, Hong WANG, Wenyuan LI, Ling NING, Hua HAN, Qiang SHEN, Shouwei JIANG, Lei LI

2022, 38(9): 2078-2083. DOI: 10.3969/j.issn.1001-5256.2022.09.024

Abstract(527)

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Abstract:
Objective To investigate the risk factors for intraoperative hypotension (IOH) in patients undergoing double plasma molecular adsorption system (DPMAS) artificial liver support therapy. Methods Clinical data were collected from 181 patients (670 cases in total) who underwent DPMAS artificial liver s...

Original Articles_Biliary Diseases

Clinical efficacy and safety of Danshu Capsule in treatment of chronic cholecystitis and gallstones

Xuelian PENG, Xiaoqing XU, Qin CAO

2022, 38(9): 2084-2090. DOI: 10.3969/j.issn.1001-5256.2022.09.025

Abstract(2464)

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Abstract:
Objective To investigate the clinical efficacy and safety of Danshu Capsule in the treatment of chronic cholecystitis and gallstones through a large-sample, multicenter, open-label real-world research. Methods A total of 9579 patients with chronic cholecystitis and/or gallstones who were treated in ...

Effect of micro-ribonucleic acid-21 on the malignant biological behavior of cholangiocarcinoma cells by targeting the PTEN/PI3K/Akt pathway

Zhe SHI, Liyuan ZHOU, Guodong ZHAO, Shugang SUN, Liang XUE

2022, 38(9): 2091-2098. DOI: 10.3969/j.issn.1001-5256.2022.09.026

Abstract(590)

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Abstract:
Objective To investigate the effect of micro-ribonucleic acid-21(miR-21) on the malignant biological behavior of human cholangiocarcinoma cell line QBC939 by targeting the protein tyrosine phosphatase (PTEN)/inositol phosphate 3-kinase (PI3K)/protein kinase B (Akt) pathway. Methods The cholangiocarc...

Original Articles_Pancreatic Diseases

Changes and formation mechanism of plasma endothelial microparticles in patients with acute pancreatitis

Didi WANG, Qiuyuan LIU, Cui HU, Bingbing WANG, Yarong WEI, Hao DING, Xiaochang LIU, Qiao MEI

2022, 38(9): 2099-2105. DOI: 10.3969/j.issn.1001-5256.2022.09.027

Abstract(437)

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Abstract:
Objective To investigate the changes and formation mechanism of plasma endothelial microparticles (EMPs) in patients with acute pancreatitis (AP). Methods Blood samples were collected from 60 patients with AP who were treated in The First Affiliated Hospital of Anhui Medical University from August 2...

Brief Reports

Clinical characteristics of non-cirrhotic portal hypertension in HIV-monoinfected patients: An analysis of 6 cases

Lili ZHANG, Jianhua HU, Chunyan GOU, Wenliang LYU

2022, 38(9): 2106-2109. DOI: 10.3969/j.issn.1001-5256.2022.09.028

Abstract(545)

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Clinical Cases Discussion

Clinicopathological features and treatment of hepatic porto-sinusoidal vascular disease with non-portal hypertensive ascites: A preliminary study

Yujiao ZHANG, Xiuhong WANG, Ying ZHENG, Anlin MA

2022, 38(9): 2110-2112. DOI: 10.3969/j.issn.1001-5256.2022.09.029

Abstract(721)

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Case Reports

Splenic infarction and repeated abdominal infection after endoscopic therapy for esophagogastric varices

Jiali MA, Lingling HE, Yu JIANG, Hongshan WEI, Ping LI

2022, 38(9): 2113-2115. DOI: 10.3969/j.issn.1001-5256.2022.09.030

Abstract(519)

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Three cases of hepatic epithelioid hemangioendothelioma

Yu ZHANG, Huali WANG, Shuming LU

2022, 38(9): 2116-2119. DOI: 10.3969/j.issn.1001-5256.2022.09.031

Abstract(838)

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Homozygous mutation in monozygotic twins in a family with hepatolenticular degeneration

Xianmei GAO, Xiaoxiao YU, Zhen YU, Linlin ZHANG, Jie YANG

2022, 38(9): 2120-2122. DOI: 10.3969/j.issn.1001-5256.2022.09.032

Abstract(519)

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Diabetes insipidus and hypothyroidism caused by hepatolenticular degeneration: A case report

Yong JIANG, Zhiguang ZHANG, Yinglan JI, Ying ZHANG

2022, 38(9): 2123-2124. DOI: 10.3969/j.issn.1001-5256.2022.09.033

Abstract(468)

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Reviews

Mechanism of action of exosomes in the development and progression of hepatitis B virus-related chronic hepatitis and hepatocellular carcinoma

Ziwei GUO, Hening CHEN, Xu CAO, Jiaxin ZHANG, Ningyi ZHANG, Qian JIN, Xiaoke LI, Yongan YE

2022, 38(9): 2125-2129. DOI: 10.3969/j.issn.1001-5256.2022.09.034

Abstract(630)

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Exosomes (EXOs) are formed by intracellular multivesicular bodies and carry a variety of biomacromolecules such as lipids, proteins, encoding and non-coding RNAs, and mitochondrial DNA. EXOs can be released in vivo by different cell types, including hepatocytes, hepatic stellate cells, and immune ce...

Research advances in the treatment of primary biliary cirrhosis

Xing LYU, Ting LI, Xiaodong SUN, Jianpeng ZHOU, Dongxia WANG, Guoyue LYU

2022, 38(9): 2130-2135. DOI: 10.3969/j.issn.1001-5256.2022.09.035

Abstract(833)

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Abstract:
Primary biliary cholangitis (PBC) is an autoimmune disease commonly observed in middle-aged women, and it may progress to liver cirrhosis and liver failure. Ursodeoxycholic acid and obeticholic acid are the only first - and second-line drugs approved by the FDA, but about 40% of patients are insensi...

Research advances in the mechanism of abnormal bile acid metabolism caused by gene mutation

Bo YI, Xue LI, Shanhong TANG

2022, 38(9): 2136-2140. DOI: 10.3969/j.issn.1001-5256.2022.09.036

Abstract(1262)

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Bile acids are synthesized and catabolized by the liver, and many factors can lead to disorders in the production, secretion, and reabsorption of bile acids, thereby causing abnormal bile acid metabolism in vivo. Common predisposing factors include hepatitis, viruses, alcohol, drugs, biliary obstruc...

Mechanism of rebalanced hemostasis in liver cirrhosis and the timing of blood transfusion and anticoagulation

Huan MA, Mei HAN, Yue ZHANG, Chunmeng JIANG, Hui LIU

2022, 38(9): 2141-2145. DOI: 10.3969/j.issn.1001-5256.2022.09.037

Abstract(630)

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Reconstructed rebalanced hemostasis exists in patients with liver cirrhosis, while such balance is unstable and can be easily broken by stress factors, which may lead to bleeding or thrombosis. There is a lack of effective strategies to prevent and solve the disrupted balance in clinic due to the co...

Influence of small intestinal bacterial overgrowth on liver cirrhosis and its treatment

Guochao NIU, Donglei SUN, Xiaolan ZHANG

2022, 38(9): 2146-2149. DOI: 10.3969/j.issn.1001-5256.2022.09.038

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Small intestinal bacterial overgrowth (SIBO) is characterized by changes in the number or species of small intestinal flora. Patients with liver cirrhosis often have intestinal congestion, edema, and delayed peristalsis and develop SIBO, which can further aggravate intestinal abnormalities. In patie...

Research advances in the early predictive factors for non-neoplastic portal vein thrombosis in liver cirrhosis

Zunlan ZHOU, Lina YANG, Qingqing LI, Hong WANG

2022, 38(9): 2150-2154. DOI: 10.3969/j.issn.1001-5256.2022.09.039

Abstract(508)

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Portal vein thrombosis (PVT) is one of the common complications in patients with decompensated liver cirrhosis, including non-neoplastic PVT and portal vein tumor thrombus after the onset of primary liver cancer. It can lead to the deterioration of liver function, aggravate the portal hypertension-r...

Clinical significance, diagnosis, and treatment of special portosystemic collateral veins in portal hypertension

Renzhi XIONG, Dongfeng CHEN, Hongli CUI

2022, 38(9): 2155-2159. DOI: 10.3969/j.issn.1001-5256.2022.09.040

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With the deeper understanding of the pathophysiological mechanism of portal hypertension and the enrichment and refinement of examination methods, special portosystemic collateral veins (PSCVs) caused by portal hypertension are constantly identified and recognized. However, early identification and ...

Efficacy and safety of programmed death-1/programmed death-ligand 1 inhibitors in treatment of hepatitis B virus-associated hepatocellular carcinoma

Ran CHENG, Xiaoyuan XU

2022, 38(9): 2160-2164. DOI: 10.3969/j.issn.1001-5256.2022.09.041

Abstract(548)

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Combined immunotherapy for hepatocellular carcinoma (HCC) based on immune checkpoint inhibitors (ICIs), especially programmed death receptor-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors, has achieved a remarkable clinical effect in clinical research and practice. Hepatitis B virus (HBV) inf...

Research advances in abnormal gluconeogenesis in hepatocellular carcinoma

Saifang LUO, Xiangming MA, Liying CAO

2022, 38(9): 2165-2171. DOI: 10.3969/j.issn.1001-5256.2022.09.042

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Tumors still perform glycolysis in the aerobic environment to accelerate the uptake of glucose and produce a large amount of lactic acid in tumor microenvironment, provide biomolecular precursors of nucleotides, lipids, and proteins for tumor cell proliferation, and inhibit the function of immune ce...

Role of Takeda G protein-coupled receptor-5 in non-viral liver diseases

Qun ZHOU, Hua ZHANG, Ping LIU, Jiamei CHEN

2022, 38(9): 2172-2176. DOI: 10.3969/j.issn.1001-5256.2022.09.043

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Non-viral liver diseases mainly include nonalcoholic fatty liver disease, alcoholic liver disease, autoimmune liver disease, and cholestatic liver disease, and the prevalence rate of non-viral liver diseases tends to increase in recent years. Takeda G protein-coupled receptor-5 (TGR5) belongs to the...

Role of lipocalin-2 in the development and progression of liver diseases

Zhengguang LIAO, Shihui WEI, Danyu DU, Li SUN, Shengtao YUAN

2022, 38(9): 2177-2181. DOI: 10.3969/j.issn.1001-5256.2022.09.044

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Lipocalin-2 (LCN2) is a secreted glycoprotein originally purified from mouse kidney cells infected with simian virus 40 and plays a key role in the control of cellular homeostasis during inflammation and the response to cellular stress or injury, and it is considered a potential biomarker for rheuma...

Role of the cytochrome P450 family in metabolic-associated liver diseases

Weiyu CHEN, Faming SHU, Han WANG, Yanggang CAO, Jin HU, Dewen MAO

2022, 38(9): 2182-2187. DOI: 10.3969/j.issn.1001-5256.2022.09.045

Abstract(2009)

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The cytochrome P450 (CYP) family is the most important drug-metabolizing enzyme in human body and is responsible for the metabolism of endogenous and exogenous compounds. As the main site of the expression of the CYP family, the liver is the metabolic center of drugs, and in recent years, the role o...

Research advances in acute pancreatitis scoring system

Xiuping LUO, Jie WANG, Qing WU, Mengbin QIN, Shiquan LIU, Jiean HUANG

2022, 38(9): 2188-2192. DOI: 10.3969/j.issn.1001-5256.2022.09.046

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Acute pancreatitis (AP) is a severe disease with an increasing incidence rate in clinical practice. Although most patients have mild pancreatitis, the fatality rate of severe pancreatitis remains at a relatively high level, and therefore, early-stage, simple, and accurate clinical scoring systems ar...

Introduction of High-quality Articles in Foreign Journals

Hepatology｜Mortality after transjugular intrahepatic portosystemic shunt in older adult patients with cirrhosis: A validated prediction model

2022, 38(9): 1973-1973. DOI: 10.3969/j.issn.1001-5256.2022.09.gwjpwzjj1

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Hepatology｜Methyltransferase 1 is required for nonhomologous end-joining repair and renders hepatocellular carcinoma resistant to radiotherapy

2022, 38(9): 2033-2033. DOI: 10.3969/j.issn.1001-5256.2022.09.gwjpwzjj2

Abstract(317)

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